Biomedical subjects

L Kepa

Publications and source records attributed to L Kepa.

At least 19 recordsLinked to original sources

PubMed1995

[Purulent neuroinfections in the course of septicemia in the years 1988-1992: personal experience].

Between 1988 and 1992 thirty patients with purulent infections of central nervous system in the course of bacterial septicaemia were treated in the Intensive Care Unit of the I Clinic of Infectious Diseases of Silesian School of Medicine in Bytom. These cases made about 32% of the total bacterial neuroinfections treated in the Clinic during that time. Imminent or existing acute respiratory insufficiency, increasing intracranial pressure, intensification of haemorrhagic diathesis and imminent septic shock were the indications to the hospitalization in the Intensive Care Unit. Neisseria meningitidis, Streptococcus pneumoniae and Escherichia coli were the most often found etiological factors in subsequently 53.33%, 33.33% and 3.34% of patients. In 10% of cases the etiological factors remained unknown. Intratracheal intubations and/or tracheotomies were carried out in over 60% of patients. About 40% of cases required assisted or controlled mechanical ventilation with the aid of ventilator (on the average 5 days). Mean time of hospitalization in the Intensive Care Unit closed in the period of 7 days. Mortality in the analyzed group was 23.33% (7 cases). Bacterial septicaemia with purulent infections of central nervous system often leads to the directly life threatening complications. Hospitalization in conditions of Intensive Care Unit affords possibilities for effective treatment and improvement of prognosis in patients suffering from these diseases.

Adult↗

PubMed1995

[Acid-base balance and electrolytes in cerebrospinal fluid of patients with bacterial and lymphocytic meningitis].

Acid-base balance and electrolytes concentration in cerebrospinal fluid (CSF) of patients with bacterial and lymphocytic meningitis were assessed. Inflammatory process causing the damage of blood-brain barrier and brains hypoxia leads to statistically significant changes of pH, pO2, bicarbonates and K+ concentrations in CSF of patients with bacterial meningitis, which in lymphocytic meningitis were not observed. Patients with fatal; outcome of bacterial meningitis showed higher CSF's acidosis and lover bicarbonates with higher K+ concentrations, which suggest deeper damage of brain hemostasis regulating mechanisms in those patients.

Acid-Base Imbalance↗

PubMed1995

[Hearing loss during the course of mumps].

Unilateral deafness as a permanent hearing injury in a patient aged 15 years with mumps is presented. Attention is paid to uncommon occurence of that complication in the course of the disease and to necessarity of taking into consideration mumps virus among other ototoxic infectious factors.

Adolescent↗

PubMed1994

[Posttraumatic meningoencephalitis in the material from the First Clinic of Infectious Diseases of Silesian Medical Academy in Bytom between 1986 and 1993].

Since 1986 to 1993 18 patients with bacterial, posttraumatic meningoencephalitis were hospitalized at the I Clinic of Infectious Diseases of Silesian Medical Academy in Bytom, and they made about 11.46% of the total purulent neuroinfections treated during that time. The group was composed of 16 men and one, 7-year-old girl, who was hospitalized twice. The course of the disease was very serious in 55.56% of cases and serious in the rest of patients. Permanent consequences subsequent to the disease like deafness, partial deafness and epilepsy were observed in 6 cases. Two patients died. After recovery gained by pharmacotherapy every patient was diagnosed with X-rays in order to find the spot of pathological connection between the cranium cavity and exterior environment, what afforded possibilities for neurosurgical or laryngological repair operation. The aim of the treatment was elimination of imminent recurrent infections of central nervous system. Accurate X-ray diagnostics and co-operation with surgical specializations enable us to improve prognosis and definitively restore patients to health after posttraumatic meningoencephalitis.

Adolescent↗

PubMed1993

[Tetanus --observations in the I Clinic of Infectious Diseases, Silesian Medical Academy in Bytom in the years 1988-1992].

Fifteen patients with tetanus were treated in the I Clinic of Infectious Diseases in Bytom in the period 1988-1992; the clinical and epidemiologic analysis was carried out of them. Severe tetanus occurred in 66% of patients and 46% of them needed mechanical ventilation. The percentage of mortality was high (46.7%). It was found that the information about tetanus was inadequate among health service personnel (physicians) and the population. Attention is called to inadequate knowledge of tetanus prophylaxis in the first line of patient's contact with the health service, which increases the risk of tetanus development. For reducing the incidence of tetanus and for improvement the efficacy of treatment this disease the authors suggest the need of adequate tetanus prophylaxis (passive and/or active immunization) in high risk injured patients.

Adult↗

PubMed1993

[Poisoning after eating sausage in observations from I Clinic of Infectious Diseases of the Slask Academy of Medicine in 1985-1992].

On the basis of our own material and the literature review the analysis of 10 cases of botulism is presented. A mild course of the disease was observed in 40%, a medium-severe course in 30% and a severe course also in 30% of patients. Fatal courses were not recorded. All patients were discharged from the Clinic in the good state of health. Etiopathogenesis, symptomatology and treatment of botulism is discussed. Attention is paid to new diagnostic method.

Adolescent↗

PubMed1992

[Encephalitis during the course of measles].

A case of measles encephalitis in a man aged 18 years was described. Attention is called to the relatively rare occurrence of such neurological complications in measles, diagnostic difficulties and good therapeutic results after corticosteroids and antiviral drugs. For reducing the incidence of measles and its neurological complications the author suggests the usefulness of protective re-vaccination against measles.

Adolescent↗

PubMed1992

[A case of side effect of Biseptol].

A case of adverse side effects of co-trimoxazole (Biseptol) was observed, with predominance of neurological changes in the clinical picture. Attention is called to the infrequent occurrence of such side effects of this drug and to the necessity of prompt diagnostic and therapeutic management of such cases.

Acute Disease↗

PubMed1991

[Meningitis and encephalitis in the years 1983-1990. Clinical observations].

From 1983 to 1990, at the I Clinic of Infectious Diseases, Silesian Academy of Medicine in Bytom, 995 patients with meningitis and encephalitis were treated; the average age was 17.86 years. After cerebrospinal fluid (CSF) examinations the patients were divided into groups. The first group consisted of patients with suppurative meningitis and encephalitis (202-20.30%), the other group were patients with aseptic meningitis (309-31.06%), a separate group consisted of patients with mumps meningitis (484-48.06% cases). In the group with suppurative meningitis and encephalitis etiological agents were isolated (Gram stain smear and/or culture of CSF) in 50.99% of cases. The most common causes of suppurative neuroinfections were: Neisseria meningitides and Streptococcus pneumoniae (in 23.76% cases). The increasing number of bacteriological tests positive results was observed during the analyzed period. The etiology of aseptic inflammation diseases of the central nervous system was defined with the help of serologic blood tests in 10-15%, and serologic confirmation of mumps meningitis was as high as 80% of cases. In the group of purulent neuroinfections, during the 8-year observation, 36 deaths occurred (17.82% of these patients). The observed tendency of the death rate decrease is concerned to be a result of better microbiological diagnostics and the possibility of an early aimed antibiotic therapy.

Adolescent↗

PubMed1991

[Guillain-barre syndrome during mumps].

A case of the Guillain-Barré syndrome in a child aged 4 years during mumps was described. Attention is called to the relatively rare occurrence of such neurological complications in mumps, diagnostic difficulties and good therapeutic results after corticosteroids.

Child, Preschool↗

PubMed1989

[Herpetic encephalitis].

On the basis of a literature review and own observations the author discusses the aetiology, pathogenesis, clinical course and treatment of encephalitis caused by herpes virus. Attention is called to the therapeutic methods.

Antibodies, Viral↗

PubMed1989

[Hearing loss in suppurative meningitis and encephalitis in our cases].

Seventeen cases of the suppurative meningitis complicated by hearing loss have been analysed clinically. Emphasis is on the possibility of such a complication in any case of the suppurative infection of CNS. The authors have shown the necessity of otolaryngological examinations in each patient, basing on their own experience and available literature. An early diagnosis and appropriate treatment produces complete recover or decreases the degree of hearing loss being a complication of the suppurative neuroinfections.

Adolescent↗

PubMed1989

[Suppurative meningitis and meningoencephalitis in patients over 60 years of age].

The course of purulent meningoencephalitis is described in 16 patients aged over 60 years. The observation showed that in these patients the pattern of the clinical manifestations was atypical and the course of the disease was very severe, leading to death in 56% of cases. The authors stress that in this age group the results of the treatment depend on possibly early diagnosis and beginning of adequate therapy.

Age Factors↗

PubMed1988