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Biomedical subjects

L Keys

Publications and source records attributed to L Keys.

6 recordsLinked to original sources

A community-based case management model for hypertension and diabetes.

Health research conducted over the past 15 years in the Mississippi Delta has continually documented a population experiencing poor health status (high rates of chronic diseases and excessive related mortalities). Both individual and health system resources are scarce in this region, posing barriers to effective chronic disease management. Two of the most significant chronic diseases that burden this population are hypertension and diabetes. To address this issue, the Delta Community Partners In Care project centering on chronic disease control was developed by a consortium of local health care institutions and supported by a national foundation. The intervention model centers on the utilization of a community-based case management approach in 13 clinical sites. Both compliance to pharmacological and individualized nonpharmacological therapy and continuity of care are stressed. A number of outcome measures showed significant improvement over the 24 month project period (N = 756).

Case Management↗

Use of the leukocyte migration inhibition assay to evaluate antigenic differences in human breast cancers and melanomas.

The leukocyte migration inhibition assay was used to compare the antigenic reactivity of 3 M KCl extracts of human tumors. Many extracts demonstrated strong reactivity with patient leukocytes, whereas others demonstrated weak or no reactivity, Extracts prepared from primary tumors or local recurrent tumors were more antigenic than extracts from involved lymph nodes or pleural effusions. The least reactive preparations were extracts made from specimens of liver metastases obtained at autopsy. A large standard extract tested at a standard concentration was useful for the evaluation of antigenic reactivity of human tumor extracts. It served as a point of reference in simultaneous tests with one blood sample from each individual, thus eliminating the influence of patient variation on extract reactivity.

Antigens, Neoplasm↗

A perinatal education consortium: improved resource utilization.

Maternal Newborn Nurse Professionals of Southeastern Michigan is an organization of nurses from more than 30 hospitals. The organization formed a committee to provide a comprehensive, cost-effective educational program for new nurses or nurses who were being cross trained, which would improve resource utilization in the region. Twice a year the organization offers a 5-day educational program covering antepartum, fetal monitoring, intrapartum, postpartum, and neonatal issues. The development, implementation, and evaluation of the program are outlined.

Costs and Cost Analysis↗