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Biomedical subjects

L Kubler

Publications and source records attributed to L Kubler.

9 recordsLinked to original sources

[Tachycardia and ensuing electrosystole].

The benign or severe nature of a ventricular extrasystole depends on a number of parameters which involve the pathophysiological mechanism of the extrasystole: re-entry, exaggerated normal or abnormal automatism and therefore the presence or absence of an underlying cardiac disease. The prognosis depends directly on the morphology, the number and the characteristics of the arrhythmia. Various investigations are often necessary to evaluate this prognosis, including 24 hour Holter monitoring, stress test and electrophysiological investigations.

Cardiac Complexes, Premature

[Syncope and fainting in patients with a cardiac pacemaker].

When a patient with a cardiac pacemaker presents with syncope or faintness, one's first thought should be failure of the pacemaker. If the abnormality is not apparent, the patient needs a full cardiological investigation, including "active" electrocardiographic recordings: magnet test, programming, or even Holter monitor should be performed in order to exclude the responsibility of the pacemaker. Modern pacemakers can fail and cause syncope, especially if they have been inadequately or incorrectly regulated. The so-called physiological (double chamber) pacemakers can induce dangerous arrhythmias. Programming of the pacemaker can avoid further operation and can relieve the syncope: acceleration to prevent twisting of the apex, increase in the power of the impulses to eliminate the defects in stimulation due, for example, to a rise in the threshold. The syncope may also be caused by an extracardiac cause: associated pathology or useless implantation; the simplicity of implantation techniques sometimes means that pacemakers are implanted in inappropriate cases.

Arrhythmias, Cardiac

[Physiologic stimulation: the future or a passing phase?].

Pacing techniques achieving normal AV synchrony are termed "physiologic". All rely on an atrial pacing or/and pacing system usually coupled with ventricular pacing. The major advantage is haemodynamic, usually related to the varying ventricular pacing rate obtained with atrial sensing systems only. Problems related to the more complex implantation technique, the cost of this system, its limited lifetime, more frequent iatrogenic complications and in particular the risk of reentry electronic "tachycardias" with the presently available models including an atrial sensing function, should limit the use of these devices to patients who really need AV synchrony if the implantation is technically possible, i.e., in our opinion, 10 to 15% of patients.

Arrhythmias, Cardiac

[A chronological linkage technic of records and use of the obtained information. Application to the functional control of cardiac stimulators].

The application of information processing to the study of the evolution of the patient's state requires the constituting of a file which contains the values of different items as functions of time. There are many methods for doing this and most of them appeal to the construction of a complex database. The technique presented in the paper paper tries at first to constitute, for each patient, some records, of which every one corresponds to a determined "operation' (the term "operation' is taken in the wide sense; example: consultation, surgical intervention,...) then to link them according to the chronological order. It has the advantage of being easy so that it may be used even on minicomputers. Furthermore, the exploitation of the resultant data file is very easy. This method is well suited to problems such as the examination of the longitudinal investigations, the treatment of records of the patients who went through several operations, etc. The application presented here is the checking of the functioning of pacemakers. We wrote on a minicomputer MITRA 15/125 transferable general program (using FORTRAN IV exclusively), which allows one to carry out the linking and to exploit the resultant file. It is so designed that the addition of new procedures involved in new applications may be very easy.

Computers

[French evaluation of cardiac stimulation].

A national enquiry into the problems related to definitive cardiac pacemakers, carried out in 1975, has yielded certain essential findings: the number of first-time implantations of pacemakers has been increasing by about 20% per annum; 92% of electrodes are currently implanted by an endocavitary technique, thoracotomy having now practically been abandoned; 90% of pacemakers implanted in 1975 were threshold models, inhibited by a QRS complex; the indications have become progressively wider, and are essentially related with the various forms of bradycardia, most frequently those due to atrio--ventricular block. In 1976, we have now reached a figure of about 200 new implantations of pacemakers per million inhabitants; those using lithium are increasingly superceding the mercury and isotope models.

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