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Biomedical subjects

L L Fellingham

Publications and source records attributed to L L Fellingham.

4 recordsLinked to original sources

Three-dimensional imaging of bone from computerized tomography.

An automatic computer technique was designed to produce three-dimensional (3D) images of bony anatomy on a cathode ray tube (CRT) from computerized tomography (CT) data. The authors transferred CT scan data of a cadaver and 11 patients to a computer system via magnetic tape. An automatic edge extraction algorithm generated an outline of bone specified by a range of CT numbers for each scan slice. These outlines were stacked in the computer and various graphics options used to represent the 3D anatomy of bone on a high-resolution CRT screen. The 3D image data were interfaced with a three-axis computer numerically controlled milling device to produce solid models of these bone images. Comparison of the dimensions of the solid models of the femur, hemipelvis, and femoral medullary canal to the actual cadaver specimen demonstrated that the models were accurate in size to within 1-3 mm. These 3D images and solid models will be helpful for preoperative diagnosis, surgical planning, and customized prosthesis manufacture in complex orthopaedic cases.

Bone and Bones↗

Three-dimensional imaging of the ankle joint from computerized tomography.

A computer system was developed to rapidly reconstruct three-dimensional (3D) images of bone from computerized tomography scans of the ankle joint. Solid models of the bones were produced from the 3D image data through the use of a computer numerically controlled milling machine. A cadaver ankle joint was scanned, and models of the distal tibia and fibula and dome of the talus were made and compared to the actual bone specimens. The measurements of the models were within 3 mm or less of the bones in all three planes (average, 1.2 mm or 5.5%). These 3D images and models of bone should allow better visualization of joint pathology and a system for preoperative planning on exact bone models to optimize the results of surgery.

Ankle Joint↗

Three dimensional imaging of bone from analysis of computed tomography data.

A computer system was developed to reconstruct three dimensional images of bone from analysis of computed tomography data. Images of bone can be made within minutes and rotated for viewing from any direction. An editing process allows visualization of the articular surfaces of any joint. Solid models of the bone images can be produced with an accuracy of 1 mm to 3 mm by interfacing the image data with a computer numerically controlled milling machine. This technology will provide better information to the surgeon for preoperative diagnosis and planning and for the design of customized implants.

Adult↗

Measurement of attenuation and scatterer spacing in human liver tissue: preliminary results.

A study measuring two quantitative parameters of human liver in vivo was performed to assess the reliability of measurement of the two parameters, and to evaluate their potential for diagnosing and grading diffuse fibrotic liver disease. The parameters measured were attenuation and "mean scatterer spacing," a measure of tissue structure. Components of variance analysis demonstrated that variation in the measured parameters was a function of the subject being examined, with significant variation noted between data acquisition sessions performed the same day. There was no significant additional variation of the measurements from week to week over a one-month period. A good correlation of the parameters with the severity of liver disease indicates that the technique may be useful in the clinical evaluation of diffuse liver disease.

Analysis of Variance↗