PubMed Health⌕ Search

Biomedical subjects

L L Kirichenko

Publications and source records attributed to L L Kirichenko.

26 records · Page 2Linked to original sources
PubMed1986

[Effect of anti-arrhythmia preparations on thrombocytic and vascular hemostasis].

Platelet aggregation, prostacyclin and thromboxane were studied in 35 individuals: 20 coronary patients with angina of effort and 15 high-risk patients before and after treatment with lidocaine and pyromecaine. Oral administration of lidocaine and pyromecaine pills considerably depresses platelet aggregation and even causes platelet disaggregation. However, lidocaine disaggregating effect is greater than that of pyromecaine. Both agents affect vascular hemostasis by reducing thrombaxane and raising prostacyclin levels. Hence, the anti-aggregant effect of anti-arrhythmic proocaines may be attributed to changes in vascular hemostasis. The results obtained are expanding the range of indications for the use of these drugs.

Adult↗
PubMed1983

[Plasma factors of blood coagulation and changes in fibrinolysis in patients with borderline arterial hypertension in thermoneutral water immersion].

The effect of 7-day "dry" immersion on the hemocoagulation system of male test subjects aged 45-55, was examined. The experiments were carried out on 15 volunteers, 11 of whom had boundary arterial hypertension (BAH) (according to the WHO classification) and 4 were healthy controls. The data obtained (thromboelastograms and coagulograms) show that "dry" immersion induces hypercoagulopathic changes in the hemocoagulation system. The BAH patients have displayed a more marked fibrinolysis depression, indicating a decline of their reserve-adaptive capabilities.

Blood Coagulation↗
PubMedDate not supplied

[Parameters of hemostasis in persons with neurocirculatory dystonia under conditions of "dry" immersion].

Twelve volunteers, aged 45-55 years, with hypertension type neurocirculatory dystonia were exposed to 7-day "dry" immersion. Plasma, platelet and vessel hemostasis was investigated. "Dry" immersion was found to stimulate hypercoagulatory changes in the above hemostasis systems. It was also shown that the test subjects developed a slow process of readaptation.

Blood Circulation↗
PubMedDate not supplied

[State of microcirculation and cellular hemostasis in men with borderline arterial hypertension during thermoneutral "dry" water immersion].

Platelet hemostasis, microcirculation, blood viscosity and lipid metabolism were examined in 18 men with borderline hypertension and 8 healthy men before, during and after 7-day immersion. The exposure to thermoneutral dry water immersion produced hypercoagulopathic changes of platelet hemostasis in the healthy and hypertensive subjects. Platelet hemostasis returned to the pretest level in the healthy subjects 2 days and in the hypertensive subjects only 5 days after exposure. Prior to immersion the hypertensive subjects showed signs of capillarotrophic insufficiency which increased after exposure. On immersion day 3 the hypertensive subjects exhibited a higher blood viscosity and a larger content of total lipids and free fatty acids. All the parameters returned to normal 2 days after immersion.

Blood Viscosity↗