[Possible etiologic role of Bacillus cereus in acute intestinal diseases of children].
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Biomedical subjects
Publications and source records attributed to L L Prokopova.
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The results of the bacteriological examination of material obtained from 71 patients with acute gastrointestinal diseases for the presence of vibrioflora, as well as the results of surveying different groups of population for the detection of vibrio-carriers are presented. The clinical and epidemiological data obtained in the course of various diseases caused by nonagglutinating vibrios are analyzed. The biological properties of nonagglutionating vibrio cultures isolated from patients and vibrio-carriers are described. The data thus obtained substantiate the necessity of carefully evaluating nonagglutinating vibrio cultures isolated from humans with due regard for the existing epidemic situation.
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The authors noticed marked vascular disorders in the capillary system, focal hemorrhages, and inflammatory, largely proliferative reactions in the stroma coupled with dystrophic and necrotic changes in parenchymal elements. The changes were found to be the most pronounced in the intestine, liver, myocardium, and in brain tissue. The degree of the lesions depended on the microorganism dosage. Provided the food contained 10(9)/g Bac. cereus, the injuring action was recorded to be more powerful, which manifested in the increased extent of vascular disorders with the hemorrhagic manifestations, thrombus formation in the vessels of the brain, heart, lungs, stomach and intestine, augmentation of dystrophic changes in organ parenchymal elements.