[Mitochondrial metabolism disorders and their implications for the locomotor system and heart. I].
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Biomedical subjects
Publications and source records attributed to L L de Mendonça.
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Reactive arthritis is a non suppurative articular inflammation following an infection elsewhere in the body. It probably occurs by interaction of external infections agents and immunological factors that mediate the host's response to the agent's antigens. The authors reviewed the role of gastrointestinal infection and infestation as a cause of reactive arthritis. Since there are no good diagnostic criteria for reactive arthritis and the investigations in this area are difficult, it is possible that many of these cases are misdiagnosed.
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The authors review the published data on antibodies to endothelial cells observed in patients suffering from diffuse connective tissue diseases. In these patients the histologic lesions are found in vessels of different sizes and localizations. It is believed that such auto-antibodies may have a role in the pathogenesis and prognosis of these disorders. The preliminary results of a study of the antigenicity of endothelial cells in mixed connective tissue disease are also presented.
Soft tissue rheumatism or "non-articular rheumatism" represents a group of diverse entities, the common feature of which is muscular stiffness and pain. It is the major cause of morbidity and loss of productive man-hours at work. There is no internationally accepted classification of the soft tissue rheumatism. On hand of an arbitrary classification of the soft tissue rheumatism the affections are divided in localized, regional and generalized conditions.
The authors review the conventional methods for the management of the soft tissue rheumatism. The success in relieving the patient's chief complaint, i.e. pain, depends on the choice of the appropriate measures that can be used without inconvenience to the patients.