[I stopped smoking without suffering. Interview by France Métivier].
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Adult↗
Biomedical subjects
L Lamothe
Publications and source records attributed to L Lamothe.
Modifications of light responses in the superior colliculus following cortical cryoblockade.
Responses to light stimuli of cells in the superior colliculus (SC) were studied in anesthetized and paralyzed rabbits after reversible inactivation of corticocollicular impulses by cooling of the visual cortex. The recording of flash-evoked responses and EEG allowed us to monitor the time course of the inactivation and its recovery. The cell's responses were measured prior to, during, and after cortical blockade. In about half of the collicular cells, disruption of cortical functions resulted in a sharp decline of collicular responsivity. All types of response were affected equally. Hence, the cortex has a global tonic excitatory impact.
Action Potentials↗
An efficient cryoprobe to inactivate cortical surfaces.
This paper describes a cryoprobe constructed of glass capillary tubes commonly employed for cellular recordings. It is inexpensive, it is easily and rapidly constructed and most importantly it can easily be adjusted to cool larger areas and tightly fit brain curvatures and gyri.
Animals↗
The treatment of the restless legs syndrome with clonazepam: a prospective controlled study.
The effect of clonazepam on the restless legs syndrome was studied in a group of 6 patients. Following a drug-free period, 3 patients received clonazepam for 4 weeks followed by placebo for 4 weeks thereafter and 3 patients received the same medication and for the same length of time but in reverse order. The effectiveness of the medication was evaluated by means of a self-rating system in which patients assigned a score daily to the degree of discomfort experienced in the previous 24 hours. Three patients improved on clonazepam but 2 of these also improved on placebo. Clonazepam was not shown to be significantly more effective than placebo in the treatment of RLS.
Adult↗