PubMed Health⌕ Search

Biomedical subjects

L Lassaletta

Publications and source records attributed to L Lassaletta.

12 recordsLinked to original sources
PubMed1992

[Nuclear magnetic resonance of anorectal malformations and persistent postoperative fecal incontinence].

We review our experience with Magnetic Resonance Imaging (MRI) in the evaluation of 6 patients showing anorectal malformation, and 4 more with persistent postoperative fecal incontinence. Preoperative sagittal, axial and coronal planes were studied with special consideration to the pelvic and vertebral structures. The excellent resolution of MRI allowed accurate identification of the pelvic musculature in all patients, including those with bizarre sacral abnormalities. MRI revealed structural anomalies not detected previously, such as teathering cord, intraspinal lipoma, presacral mass and renal malformation. In our institution, MRI has replaced the CT scan in the study of patients suffering of persistent fecal incontinence. In non operated on cases of anorectal malformations, MRI determines with extraordinary accuracy the location of the rectal atretic pouch, the actual pelvic muscular quality, and the detection of previously unsuspected associated anomalies.

Anal Canal↗
PubMed1991

[A case of total intestinal aganglionosis. 2 years of survival].

A two-year-old male is presented. Small bowel aganglionosis was proved to extend to 3 cm below ligament of Treitz. Gastrostomy and ileostomy was done. He received his caloric intake by cyclic home parenteral nutrition trough implantable venous system. At eighteen months of age, intestinal transplantation was refused and reoperation was done. The child underwent Ziegler's miotomymiectomy on 60 cm of aganglionic jejunum. Now at twenty seven months of age he receives cyclic parenteral nutrition, and enteral feedings are being increased slowly. The weight/height was at 91 per 100 standard, intestinal motility appears much better on contrast study and he is developmentally a normal child.

Biopsy↗
PubMed1990

Association of juvenile and adenomatous polyposis with pulmonary arteriovenous malformation and hypertrophic osteoarthropathy.

The juvenile form is the usual type of colonic polyp seen during childhood. However, mixed forms associating juvenile and adenomatous polyps have been reported. A syndrome including the association of generalized juvenile polyposis, pulmonary arteriovenous malformation, and hypertrophic osteoarthropathy has been described in three cases; however, this is the first report of the association of mixed juvenile and adenomatous polyposis, pulmonary arteriovenous malformation, and hypertrophic osteoarthropathy.

Animals↗
PubMed1990

Abdominal mass: "fetus in fetu".

A female newborn presented a mass in the left upper abdominal quadrant. It was removed by surgery and contained two independent fetuses. Dissection and radiological study of the fetuses showed an axial skeleton and long bones. It corresponds to the generally recognized diagnostic criteria of fetus in fetu.

Abdomen↗
PubMed1989

[Effect of prostaglandin (PGE2) in biliary atresia].

We studied the choleretic effect of Prostaglandin E2 (PGE2) in patients with biliary atresia. In the last four years PGE2 was used in ten cases with extrahepatic biliary atresia. All of them were treated by Kasai technique and temporary exteriorization of the bilioenteric conduit, permitting analyses of the postoperative bile flow. Mean age al operation was 50 days (range 30-70 days). The histology studies of liver and porta hepatis showed severe hepatic fibrosis in three patients, moderate in seven, bile ducts less than 100 mu in five and more than 100 mu in another five. The mean postoperative bile flow was 15 c.c./day (range 0-30 c.c.). We used PGE2 during postoperative period because the bile excretion was partial or total stopped (PGE2 0.125 mgr./kgr./day). In six cases the bile flow increase until 90 c.c./day (range 40-160 c.c./day) and four patients no response. Eight patients are alive, four without jaundice with normal hepatic function (serum bilirubin 1.04 mgr./dl) and four are waiting for liver transplantation. Two have died 7 and 30 months after Kasai procedure. The long-term follow-up was between 6 to 53 months. In conclusion the PGE2 has choleretic action in biliary atresia and could be a coadjuvant treatment to improve the bile flow.

Biliary Atresia↗
PubMed1979

[Neonatal laceration of liver and spleen (author's transl)].

A very unusual observation of survival after surgical treatment of neonatal maceration of liver and spleen is reported. The patient had a normal birthweight and the only possible etiologic factor was a oxitocin-induced rapid delivery. The literature on this topic is reviewed.

Birth Injuries↗
PubMed1978

[Effects of parenteral nutrition solutions on the venous walls (an experimental study) (author's transl)].

Lesions (thrombosis, intimal damage, perivascular inflammation) of the marginal ear vein of domestic rabbits were studied 48 hours after infusions of parenteral feeding solutions administered through a butterfly-type 25 needles. Six-hour infusions with a rather diluted solution (12 g dextrose, 1.25 g. aminoacids, 1.5 mEq., Na, Cl, K and PO4 and 1.5 mEq. Ca and Mg per 100 ml.) with osmolality of 930 and pH of 6.9 were slightly harmful, while the lesions were considerable after 12-hours infusions. A more concentrated solution (15.83 g. dextrose, 2.08 g. aminoacids, 2.5 mEq. Na, Cl, K and PO4 0.2 MEq. Ca and Mg per 100 ml.) with osmolality of 1,600 and pH 6.7 produced severe lesions both after 6 and 12-hours infusions. Similar results were obtained with a mixture of this solution with intralipid at clinical doses (4 g. fat for 100 ml. of solution). This mixture had 1,280 mOsm/1. and pH of 6.7. Rather surprisingly the lesions were even more marked when intralipid alone was infused (osmolality 317, pH 7.5). These results lead to the conclusion that practically all fluids used for parenteral feeding purposes either centrally or peripherally, are considerably harmful for the venous wall after a few hours of infusion, probably due to their shifts from isoosmolality and chemical neutrality. Specially puzzling was the harmful local effect of the otherwise well tolerated intralipid.

Animals↗
PubMed1978

[Choledochal cyst (author's transl)].

This paper reports six pediatric patients with congenital choledochal cyst. From the long-term follow-up results of the six patients authors conclude that primary excision of the choledochal cyst and Roux hepatic jejunostomy are the first choice treatment for this lesion. However, it may not be possible in all cases, and choledochocystoenterostomy would then be useful as a second choice.

Biliary Tract Diseases↗
PubMed1976

Arterial endothelial changes after ischemia and perfusion.

The effects of six hours of ischemia and six hours of perfusion with 10 per cent dextrose and water solution, Sacks' solution and Intralipid on the endothelium of common femoral arteries in dogs were examined by light and by scanning electron microscopy and compared with normal arteries. Arteries that were ischemic or perfused with 10 per cent dextrose and water solution or Sacks' solution showed a flattening of the normal linear convolutions and extensive crater formation, with fragmentation and even complete loss of endothelial cells in many areas. The more severe changes occurred in perfused vessels. Fibrin and platelets covered the luminal surface in many areas in which there was extensive injury to the endothelium. Light microscopy revealed thickening of the internal elastic membrane and intimal fibrosis. Results of biopsies performed two weeks after perfusion showed slight, although incomplete, improvement in the structure of the endothelium. Arteries perfused with Intralipid had thickening of the intima with a proliferation of plump cells orientd linearly over the surface but with an absence of craters. Results of present studies confirm the observations of other investigators that injury to endothelial cells may be produced by ischemia and that perfusion with various solutions may produce an even more severe alteration in structure of the endothelial cell which does not return to normal within two weeks. The origin of new endothelial cells is not demonstrated by this study.

Animals↗