L Le Bodic — Page 5 | PubMed Health

PubMedDate not supplied

[Importance of using hematoporphyrine derivate in the destruction of adenocarcinomas with Nd Yag or argon lasers].

As the hematoporphyrin derivate photochemical properties have been known for many years, this study tries to appreciate the laser beam effect on experimental tumors previously sensitized by H.P.D. Colic adenocarcinoma cells are grafted on mice. On the 10th day tumors are photocoagulated. Previously the mice were divided into 4 groups: G 1: H.P.D. intra-venous injection on the 9th day followed by a Nd Yag laser photocoagulation; G 2: Nd Yag laser only; G 3: H.P.D. intra-venous injection on the 9th day followed by an argon laser photocoagulation; G 4: argon laser only. The G 1 and G 2 study shows that, when Nd Yag laser is used, H.P.D. alters the type of necrosis obtained and the action depth. The G3 and G4 study shows that, when argon laser is used, H.P.D. does not alter the type of necrosis obtained but greatly increases the action depth.

Adenocarcinoma↗

PubMedDate not supplied

[Quality of life and ileo-anal anastomosis with pouch. Results of a prospective series of 35 surgically treated cases of hemorrhagic rectocolitis. Proposal for a score of quality of life].

Ileal-pouch anal anastomosis (IPAA) following coloproctectomy avoids permanent ileostomy, and allows complete excision of diseased mucosa in ulcerative colitis (UC) and adenomatous polyposis. Preserving normal intestinal pattern, the goal of IPAA is to improve quality of life for patients. This study was designed to measure the impact of IPAA on quality of life in a series of 35 surgically treated UC. Four fields of quality of life were explored: diet, professional activity, sport practice, sexual activity. Interview with independent observer and prospective follow-up allowed to establish a score from 0 (excellent quality of life) to 19 (bad quality of life). In the same time, functional score evaluating pouch evacuation and continence was established (0 = excellent function, 30 = bad function) to be compared to quality of life. The series included 35 IPAA in function for more than 6 months (mean follow-up = 46 +/- 31 months), performed for UC (14 females and 21 males, mean age: 34 y-a). Respectively 30 (86%) and 5 (14%) of the patients had an excellent and fair quality of life, according to the scoring system: 25 had no diet, all but one had a normal professional activity and all were satisfied of sport practice; 33 had no sexual disturbances related to IPAA, but 3 female patients complained of infertility. Functional results were excellent, fair and bad respectively in 25 (72%), 9 (26%) and 1 patients: stool frequency was 4.6 +/- 2 per day, 60% of patients having no nocturnal emission, and 90% being able to delay for more than 1 hour.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗