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Biomedical subjects

L Lemke

Publications and source records attributed to L Lemke.

At least 19 recordsLinked to original sources

[Retinal hemodynamics in cerebrovascular accidents].

In 32 patients the times of retinal passage were determined in 112 examinations immediately after cerebrovascular insult and following in daily intervals. In this case after the insult a significant change of the retinal haemodynamics could be observed: the bolus-tension time and the time V2 showed a continuous deterioration of the blood supply of the retina possibly parallel to the cerebral haemodynamics. Furthermore it was shown that the initial prolongation of the arm-retina-times over 17 seconds refers to serve cerebral lesions with poor prognosis. It seems that the method described is not suitable for the preliminary diagnosis of extracranial vascular processes: In acute extracranial vascular occlusion we found equality of the sides of the inflow of dye as well as differences of the sides of more than 30 seconds in free extracranial vascular lumina.

Adult↗

[Non-invasive cardio-circulatory diagnosis with the help of retinal dye clearance].

Using the fluorescence microscopy the times of retinal passage A 1, V 1, A 2 and V 2 were determined in 36 patients with heart diseases. They were compared with different haemodynamic parameters, in 27 patients with intracardially got circulatory indicators. The time of the renal circulation (V 1-A 1) in certain respect correlastes with the time volume of the heart, the bolus-extension time (A 2-A 1) with the degree of insufficiency of the heart. The value V 2 appears as a very sensitive, unspecific measuring value, which is also influenced by the peripheral haemodynamic situation. The method seems to be suitable as non-invasive method. Its advantages consist in the small temporary, personal and material expenditure.

Coronary Circulation↗

[The passage of dyes through the retinal vessels].

Examinations of the retinal haemodynamics after injection of fluorescein sodium were performed on three groups of test persons, in normal persons, patients with diseases of the retina as well as patients with organic heart defects. In the group of heart diseases statistically significant disturbances of the retinal haemodynamics could be proved, which the retina tolerates without any lesion. In comparison to this retinopathies with severe changes of the fundus show only slight disturbances of the haemodynamics. These do not give the possibility of the explanation of the changes of the fundus.

Adult↗

[Light coagulation in central and paracentral choroiditis (author's transl)].

Since 1966 photocoagulation has been performed in 52 cases and 54 eyes of choroiditis located on the posterior pole. The course of the cases treated is compared with a control group treated with drugs. Photocoagulation shortens the duration of the acute inflammatory process, decreases the frequency of recurrences by about 40% and improves the visual prognosis. The follow-up 1 year to 9 years later (average 7 years) showed in the control group a visual function of 0.5, in the treated group of 0.8.

Acute Disease↗