PubMed Health⌕ Search

Biomedical subjects

L Lenzini

Publications and source records attributed to L Lenzini.

At least 19 recordsLinked to original sources
PubMed1980

Studies on bronchoalveolar cells in human diseases. II. General morphology and ultrastructure of pulmonary macrophages and small mononuclear cells in sarcoidosis.

Data are presented from light and electron microscopic studies on bronchoalveolar lavage (BAC) in sarcoidosis, with particular emphasis on the ultrastructural morphology and functional characteristics of pulmonary macrophages (PM) and small mononuclear cells (SMC). Light microscopy showed an average of over 77% of the BAC to be PM, range 99-51%. SMC populations were also extremely variable. These variations may relate directly to the degree of disease activity. Electron microscopy demonstrated a wide range of morphological and implied functional (biosynthetic and phagocytic) characteristics of PM. Some of these are morphologically comparable to cells found in tissue granulomata. Our ultrastructural study has shown that the SMC population is made up of lymphocytes, monocytes and cells with intermediate characteristics (precursors).

Adult↗
PubMed1978

Studies on bronchoalveolar cells in humans. I. Preliminary morphological studies in various respiratory diseases.

A preliminary investigation has been carried out on bronchoalveolar cells obtained following lavage in various respiratory diseases. Of 23 cases observed, 7 have been studied in detail, 6 cases provided insufficient material for investigation, and the data obtained from the remaining 10 cases were inconclusive. Considerations are made with regard to the value of bronchial lavage in clinical diagnosis and cell studies.

Adolescent↗
PubMed1977

The spectrum of human tuberculosis.

Clinical, morphological and immunological studies of human tuberculosis have enabled the spectrum of the disease to be determined. We have investigated the cell-mediated immune responses by means of skin tests and leucocyte migration inhibition to PPD, and the humoral immune responses by means of immunodiffusion and haemagglutination tests. Patients with tuberculosis can be classified into two polar groups--reactive (RR) and unreactive (UU), the former showing good cell-mediated immunity and little or no antibody formation and the latter poor cellular responses and exuberant antibody production. The intermediate forms show characteristics of the neighbouring polar groups. The existence of a spectrum of immune response in tuberculosis, which has long been suspected, is now demonstrated.

Adolescent↗