In vivo prostaglandin concentrations in human preovulatory follicles.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to L Levesque.
Explore the source record for details and available documents.
Follicle puncture with oocyte harvest or ovarian inspection for an early corpus luteum was carried out in 13 patients undergoing laparoscopy during routine infertility workup. Laparoscopies were carried out 28 to 38.5 hours after the onset of the luteinizing hormone surge so that there would be a concentration of data around the expected time of ovulation. A rapid luteinizing hormone assay was used. All the corpora lutea were found 38 hours or more after the onset of the luteinizing hormone surge. Between 28 and 38 hours after the onset of the surge, intact follicles containing oocytes in various stages of maturation were found.
The temporal relationship of oocyte maturation to endogenous luteinizing hormone (LH) in vivo throughout the preovulatory period has not been previously reported. In order to study in vivo oocyte maturation follicular aspiration was carried out from 4 to 38 hours after the onset of the LH surge. Oocytes were obtained in 72% of cases. If oocytes were harvested more than 18 hours after the onset of the LH surge, resumption of meiosis had occurred. Twenty-eight to thirty-eight hours after the onset of the LH surge preovulatory oocytes in metaphase II were obtained. A corpus luteum was found 38 hours after the onset of the LH surge.
Trisomy 11q in a 13-month-old patient with severe mental deficiency, generalized dysmorphia, and a cardiac anomaly represents a previously unrecognized form of malsegregation of the frequently observed translocation t(11;22)(q23.1;q11.1).
Twenty Sprague-Dawley rat pups received injections of 2 mg/g, 4 mg/g monosodium glutamate (MSG) or physiological saline (mean volume) subcutaneous daily for the first 10 days of life. At 70 and 90 days, rats were tested for open-field and aggressive responding, respectively. Body weights were recorded throughout development. When compared to the control group, results indicated: (1) significantly lowered body weights for both MSG-injected groups with the 4 mg/g group showing the greatest weight suppression, (2) a significant decrease in open-field activity for the 2 mg/g MSG group, with the 4 mg/g MSG group not quite reaching a statistically significant decreases, (3) significant decreases in aggressive responding of both MSG groups. The decrease in open-field activity supports the type of MSG-induced behavioral suppression previously reported for rodents, while an MSG-induced decrease in aggression has not been previously documented.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.