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L Lipska

Publications and source records attributed to L Lipska.

5 recordsLinked to original sources
PubMedDate not supplied

Changes of thymidine kinase (TK) during adjuvant and palliative chemotherapy.

UNLABELLED: Thymidine kinase is involved in nucleic acid synthesis and is, therefore, considered to be an important proliferation tumor marker. For this reason, we monitored this marker in the course of colorectal cancer chemotherapy. MATERIALS AND METHODS: We examined thymidine kinase (TK) levels in 30 patients with colorectal cancer who underwent adjuvant or palliative chemotherapy (CHT schemes). The condition for being included in the study was a minimum of 3 cycles of chemotherapy. TK was always assessed with radio-receptor analysis, before and after every chemotherapy cycle, together with other tumor markers. RESULTS: From the monitored tumor markers, only TK changed typically in the course of chemotherapy. In adjuvant chemotherapy, it was mostly low at the beginning of the cycle and its values usually increased considerably at the end. On the other hand, in palliative chemotherapy the dynamics of TK varied mainly depending on the effect of the therapy. Other tumor markers showed nonstandard behavior and minimal correlation with TK changes. CONCLUSION: Thymidine kinase seems to be a suitable parameter for monitoring the effect of adjuvant and palliative chemotherapy in colorectal cancer.

Chemotherapy, Adjuvant↗
PubMedDate not supplied

[Survival time after stroke].

The probability of survival after a first stroke is as a rule small because less than half patients survive one year. The greater probability of survival observed in the group of males depends probably on a younger age of the patients at the time of disease onset. The probability of surviving the first day, first month and first year is lowest in cerebral haemorrhage. The prognosis is best in subarachnoid haemorrhage and cerebral infarction. The youngest patients were in the group of subarachnoid haemorrhage (45 years mean age) and in the group of cerebral haemorrhage (55 years), in the other groups of stroke the mean age was about 70 years. Coexistence of hypertension and atheromatosis decreased most the probability of one-year survival.

Adult↗
PubMedDate not supplied

[Incidence of stroke among the adult population of the Cracow-Nowa Huta district].

The analysis of the first admission to hospitals showed that nearly 90% of patients with manifestations of brain stroke were referred to neurological departments. The indices of incidence calculated on the basis of first admissions were usually low, which was due to young age of the studied population. A comparison of the incidence indices standardized or age in the Nowa Huta values were nearly identical. The pattern of diagnoses resembled that reported by other authors. The most frequently observed form of brain stroke was infarction, diagnosed in over 50% of cases.

Adult↗