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Biomedical subjects

L Lismer

Publications and source records attributed to L Lismer.

9 recordsLinked to original sources
PubMed1996

Carcinoma of the bladder in patients under 25 years of age.

A review of our records between 1971 and 1995 identified 6 patients (4 male and 2 female) with transitional cell carcinoma of the bladder who were less than 25 years of age (mean age 18.6, range 10-22). Five patients presented with gross haematuria, one with microscopic haematuria, and two presented with recurrent urinary tract infection. All tumours were low grade and low stage and were associated with excellent prognosis. Transurethral resection or fulguration was the treatment of choice. This study supports the contention that transitional cell carcinoma of the bladder is a less aggressive disease in patients under 25 years of age.

Adolescent↗
PubMed1991

Cellular B-2 microglobulin expression as a prognostic indicator in renal cell carcinoma.

The expression of B-2 microglobulin (B-2M) on tumor cells and their normal cell counterparts in 39 patients with renal cell carcinoma was studied and correlated to tumor stage and survival. The median survival time of patients with localized disease (stage I) whose tumors expressed B-2M was 10.2 years while the median survival time for patients whose tumors did not express B-2M was only 3.6 years (p less than 0.001). For patients with more advanced disease (stages II, III, IV) whose tumors expressed B-2M, median survival time was 3.6 years compared to 2.0 years in patients whose tumors did not express B-2M, a non-significant difference. It is suggested that the tumor cell membrane expression of B-2M may serve as an indicator of good prognosis in early renal cell carcinoma.

Adolescent↗
PubMed1987

Squamous cell carcinoma of the renal pelvis with sarcomalike stroma: a light and electron microscopic study with immunohistochemical analysis.

Primary neoplasms of the renal pelvis are rare. Most are malignant, and most of these are transitional cell carcinomas. We report the unusual occurrence of a squamous cell carcinoma with sarcomatoid stroma arising from the renal pelvic mucosa in a patient with renal lithiasis. Immunohistochemical stains for keratin intermediate filaments failed to demonstrate their presence in the spindle cell portion of the tumor. Transmission electron microscopic study did not reveal structures of an epithelial nature in these same cells. Our findings support the contention that the spindle cells of the stroma are not squamous in nature, but represent either a reactive or a neoplastic transformation of these underlying stromal elements.

Carcinoma, Squamous Cell↗
PubMed1987

Vascular polyps of ureter associated with megacalycosis and nephrolithiasis.

Multiple benign vascular polyps of the ureter are rare, and the associated congenital megacalycosis and nephrolithiasis are very uncommon. Herein we report a case with vascular polyps of the right ureteropelvic junction dissociated with extensive hydronephrosis which was considered to be megacalycosis. Clinical features and treatment modalities are reviewed.

Adolescent↗