Biomedical subjects
Publications and source records attributed to L Lopez-Gomez.
Based on experimental and clinical evidence of central pain produced by hyperactivity of deafferented neurones and associated with irritative foci at thalamic or cortical levels, stereotactic low-dose (10 Gy) radiosurgery has been performed in 3 patients with central pain syndromes. SEEG findings and results of stereotactic radiosurgery on painful conditions are presented and mechanisms of action discussed.
In 17 epileptic patients, most of them with seizures of partial type but with diffuse or focal alternating abnormalities in the electroencephalographic recordings, chronic implantation of subarachnoid electrodes was performed. Through two bicoronal burr-holes and under fluoroscopic control, 13 to 19 insulated monopolar flexible electrodes were introduced in the subarachnoid space, conducting them either to standardized cortical targets, or concentrating them in that area of interest showed by conventional EEG. The electrodes were placed bilaterally and symmetrically, and remained implanted for 10 days. During this period, the activity of multiple foci, the reciprocal dependence between them, its reaction to cortical electric stimulation, barbiturate administration and sleep, were studied. No morbidity was found. Because of the simplicity and safety of this technique, it appears to be a good diagnostic method placed between conventional EEG and stereoelectroencephalography.
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