[Sleep disorders in clinical practice].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to L Ludewig.
Explore the source record for details and available documents.
On the basis of sleep-polygraphic examinations of twelve alcoholics over a period of six days is given on the sleep behaviour during alcohol withdrawal. The study showed the withdrawal symptoms described in the literature, such as withdrawal insomnia, REM rebound and persisting shortening of the deep sleep time, in ten patients whereas in two cases the examinations had to be interrupted in the third night because of a withdrawal delirium. In these cases, however, an almost 100 per cent REM occurrence was seen from the first night. The significance of these findings with respect to an early prediction of the outbreak of the delirium and for the pathogenesis of the delirium in general is discussed.
Clozapin holds pharmacologically and clinically a special position among psychoactive drugs. By means of EEG examinations in 25 patients without and with Clozapin it could have been proved statistically that the distinctly marked changes can unambigously traced back to Clozapin medication. These role is in regard to localization explainable by pharmacologically assumed brain stem efficiency of the medicament. The increase of beta activity which was also found and which is not typical for neuroleptics can be explained in connection with the central anticholinerg action component.
Explore the source record for details and available documents.
A report is given on two patients with delirium tremens and alcoholic Wernicke's encephalopathy in whom highly pathologic curve behaviors of the early acoustically evoked potentials were found. Methodological and practical-clinical consequences are seen.