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Biomedical subjects

L M Dean

Publications and source records attributed to L M Dean.

17 recordsLinked to original sources

Cerebral hemorrhage in alloimmune thrombocytopenia.

Intracranial hemorrhages are rare in term infants. We describe such an infant born with multiple foci of intraparenchymal hemorrhage in various stages of maturation, caused by maternal platelet-specific anti-PlA1 antibodies that were delivered transplacentally to the developing fetus.

Blood Platelets↗

The intracranial venous system in infants: normal and abnormal findings on duplex and color Doppler sonography.

Venous hypertension has been implicated as an important factor in the pathogenesis of neonatal brain injury under a variety of circumstances, such as periventricular hemorrhagic infarction in the preterm infant [1], cerebrovascular injury after treatment with extracorporeal membrane oxygenation (ECMO) [2], and thrombosis of the superior sagittal sinus. Although duplex and color Doppler sonographic techniques have been used to evaluate the intracranial arterial tree for several years, little attention has been paid to the role of Doppler techniques in the evaluation of the cerebral venous system. We describe the appearance of the normal infantile cerebral venous system on color and duplex Doppler sonograms and present a spectrum of abnormalities in venous hemodynamics in critically ill infants with the goal of familiarizing readers with the clinical potential of this technique.

Central Venous Pressure↗

Only the cleaner.

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Attitude of Health Personnel↗

Correlates of depressive mood among normals.

In order to determine the correlates of depressive mood, members of a women's volunteer organization were surveyed by a mailed questionnaire that included the Depression Adjective Check List (DACL) Form E and 14 depression-related measures. Correlations are presented and discussed. Highest correlations are with measures whose relationship to depressive mood are most clear.

Adult↗

Interpersonal touch among adults in cafeteria lines.

Previous studies have indicated that interpersonal touch decreases with age. In the present study 1012 pairs of college students and 212 pairs of elderly subjects were observed in cafeteria queues. Instances of touch were recorded along with sex, race, and body parts used to touch and touched. College students segregated themselves by race and sex just as the younger students had been observed to do in previous studies. Unlike all previous studies the elderly subjects did not segregate themselves by gender. For college students, touch was highest for female to male combinations; blacks were more likely to touch other blacks and least likely to touch whites. Touch was more likely among elderly subjects for female to female interactions than it was for college students, but there were no differences for the other gender combinations. In college students personal body areas were used to touch those of different gender while impersonal body areas were used to touch those of the same gender; personal body areas were more likely to be touched by others of the other gender. For elderly subjects there were no differences in frequencies with which personal or impersonal areas were involved in touch in relation to gender for either area used to touch or area touched.

Adult↗

Drug abuse: a manifestation of the cyclic nature of human behavior.

The authors conclude that a cyclic pattern of drug use behavior can be documented in a given population. While such a study provides a microcosmic view of such behavior, it is postulated that this same cyclic pattern was experienced in the macrocosm of society at large by drug-abusing populations over centuries past.

Adult↗

Social aspects of venereal disease aboard a U.S. navy destroyer.

This paper describes the social characteristics of venereal disease patients aboard a US Navy destroyer. The research team administered questionnaires to 247 crew members at the outset of the ship's 7 month-overseas deployment. When the ship returned to home port, the research staff gathered demographic and occupational information plus disciplinary records, job performance ratings, and complete dispensary visit information for the deployment period. The morbidity data indicated that 48% of the entire crew experienced at least one case of VD, and of these VD patients, 38% had multiple infections. A set of variables that best predicted VD incidence was determined by means of multiple regression analysis. These variables included disciplinary record, pay grade, division or type of job ("blue-collar" versus "white-collar"), and education. Other variables that correlated with VD incidence were age, length of service, marital status, performance ratings, and verbal aptitude scores.

Adolescent↗

Effects of crowding of mice on humoral antibody formation and protection to lethal antigenic challenge.

The effects of grouping (crowding) on humoral antibody response to typhoid paratyphoid vaccine and subsequent protection from a minimal lethal challenge dose of Salmonella typhimurium were studied in white Swiss-Webster mice. The data show a trend between the degree of crowding and antibody response. Geometric mean titers of high density grouped mice were significantly lower than the geometric mean titers of the less crowded mice. Also, there were significantly less antibody responders in the high density grouped mice than in the less crowded mice. However, challenged with a minimal LD50 dose of Salmonella thphimurium, no deaths occurred in the immunized study group, regardless of measurable antibody level. In the nonimmunized controls, which were under the same stressor conditions, there was a significant difference between the level of crowding and death to challenge. The data show that nonimmunized mice in this study exhibited a marked increase in susceptibility to an infectious agent when under the stressor effect of crowding.

Animals↗

Effect of three teaching methods on a nursing staff's knowledge of medication error risk reduction strategies.

The authors' purpose in this study was to (1) compare the effects of three teaching methods on registered nurses' and licensed practical nurses' knowledge of medication error risk reduction strategies, and (2) to compare registered nurses' and licensed practical nurses' knowledge of medication error risk reduction strategies using a pretest/posttest design. Registered nurses (n = 129) and licensed practical nurses (n = 21) employed by two hospitals constituted the study sample. Subjects were assigned alternately to three intervention groups: videotape (n = 50); instructional booklet (n = 50); and lecture (n = 50). A 38-item test, including true-false, multiple choice, matching items and dosage calculation problems, was administered to subjects in each group before and after the teaching intervention. On the basis of the results, there was no statistically significant difference in total knowledge scores for the three intervention groups (F = 2.07, P = 0.130). Staff development instructors should consider the advantages of a videotape and instructional booklet over the time-intensive lecture strategy.

Adult↗