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L M Fantozzi

Publications and source records attributed to L M Fantozzi.

31 records · Page 2Linked to original sources

Holoprosencephalic disorders. Case report of a semilobar type.

A child with microcephaly, facial dysmorphisms, seizures, and congenital cardiopathy is presented. On the basis of skull x-rays, electroencephalogram, transillumination of the head, and computed tomography (CT) scan, the diagnosis of semilobar holoprosencephaly was made. The heterogeneous etiology of the disorder is discussed in order to evaluate the recurrence risk. The usefulness of CT scan for the classification in the different types of holoprosencephaly is stressed.

Brain↗

Early angiographic and CT findings in patients with hemorrhagic infarction in the distribution of the middle cerebral artery.

Hemorrhagic infarction subsequent to ischemic brain damage, even if small, slight, or marbled, can be detected by CT. The mechanisms that give rise to this transformation in humans are not well elucidated. Previous reports indicate that hemorrhagic infarction is most common in embolic stroke and large infarcts, and can worsen the clinical state of ischemic patients. We examined 36 patients with supratentorial ischemic signs and symptoms within the first hours after onset. CT was used to judge if hypodensity on early CT studies might predict the development of hemorrhagic infarction. Angiography was used to observe the site of arterial occlusion, the state of collateral circulation, and the mechanisms of late reperfusion. Hemorrhagic infarction was present in 18 of our 36 patients. Angiography revealed occlusion of the middle cerebral artery or internal carotid artery (three cases) in all patients. Hypodensity was present on early CT studies in all of the 18 patients who developed hemorrhagic infarction. The finding of hypodensity on CT studies performed soon after embolic ischemic stroke is strongly predictive of hemorrhagic transformation.

Brain Ischemia↗

Correlation of angiographic and sequential CT findings in patients with evolving cerebral infarction.

The usefulness of CT and angiography for predicting the final ischemic brain damage resulting from supratentorial ischemic stroke was evaluated in 36 patients. CT was performed within 4 hr and angiography within 6 hr after the onset of symptoms. CT was used to assess the site and size of parenchymal brain damage and angiography was used to evaluate the cerebral circulation. A 3-month follow-up CT study was used to determine the site and size of final ischemic damage. Angiography was normal in six patients and showed complete occlusion in 30. Angiographic findings in patients with arterial occlusion were classified as either internal carotid artery occlusion or middle cerebral artery (MCA) occlusion. MCA occlusions were subdivided into occlusion before the origin of internal lenticulostriate arteries (type 1), occlusion beyond the origin of these branches (type 2), occlusion at the bifurcation of the main trunk (type 3), and occlusion of the peripheral branches (type 4). Collateral blood supply was also studied. Early CT findings were positive in 25 of 36 patients; the lentiform nucleus alone, the lentiform nucleus and the cortex, or only the cortex were involved. In all patients with positive early CT findings, angiography showed an arterial occlusion, often located in the main trunk of the MCA. Involvement of the lentiform nucleus on early CT was always seen in patients with internal carotid artery or type 1 MCA occlusion.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

The usefulness of dynamic CT in patients with aneurysm of Willis circle. Comparative study with the angiography.

The diagnosis of cerebral aneurysm is currently based on the angiographic data. We have tried to evaluate the usefulness of a less-invasive examination, such as the dynamic-CT, in the diagnosis of intracranial aneurysm and of the possible and concomitant subaracnoid haemorrhage. The CT examination is useful in the diagnosis of both subarachnoid haemorrhage and giant trombosed aneurysm. It is less reliable than the angiography as regard to aneurysm of small dimension.

Adult↗

[Computerized tomography in the evaluation of neurologic complications of preventive therapy of acute lymphatic leukemia].

The authors examined by means of computed tomography 12 patients with ALL treated with radiotherapy combined with cytostatic chemotherapy and presenting clinical signs of CNS damage. The CT scan findings are correlated with clinical signs, mainly distinguishing between symptoms of either diffuse or focal damage. An attempt is made in order to evaluate the possible role of Methotrexate and X-Ray therapy in the pathogenesis of the CNS lesions.

Adolescent↗