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Biomedical subjects

L M Gerber

Publications and source records attributed to L M Gerber.

24 records · Page 2Linked to original sources

Gains in life expectancies if heart disease and stroke were eliminated among Caucasians, Filipinos and Japanese in Hawaii.

Life tables were constructed based on all deaths in Hawaii occurring between 1968-1972 for Caucasians, Filipinos and Japanese. Gains in life expectancies to be attained if coronary heart disease (CHD) and cerebrovascular accidents (CVA) were eliminated were presented by sex and ethnic group. The expectation of life at birth for both males and females is greatest for Japanese, followed by Filipinos and then Caucasians. The gain in life expectancy by eliminating CHD would not benefit Caucasians while Filipinos would benefit the most from the elimination of CVA. For all ethnic groups and both sexes, the gain in expectation of life due to the elimination of CHD is more than were CVA eliminated as a cause of death.

Actuarial Analysis↗

Effects of sample selection on the coincidence of hypertension and diabetes.

The occurrence of both hypertension and diabetes in patients at a general medical clinic at a university center and within a work-site community has been determined. In addition, the course of such patients for four years following presentation has been observed. The combination of hypertension and diabetes appeared more frequently, was expressed by greater severity, and coincided with a higher observed morbidity among the hospital clinic patients than among the work-site population. These findings regarding the prevalence and natural history of these coexistent diseases reaffirm that the source of a selected population can significantly affect the pattern of disease expression observed and, therefore, limit the capacity to extrapolate results from one population to another.

Blood Glucose↗

Waist-to-hip ratio as an index of risk for hyperglycemia among hypertensive patients.

Participants in a systematic antihypertensive care program were examined to determine whether the site of fat predominance--measured by the waist-to-hip ratio--is related to hyperglycemia in patients taking diuretics. Among 1,044 hypertensive patients meeting a set of selection criteria, 22 men who developed hyperglycemia during a mean treatment period of 25.6 months were identified and individually matched for age, race, body mass index, and duration of diuretic treatment to a comparable group of hypertensive patients who remained normoglycemic. The mean waist-to-hip ratio was higher among the hyperglycemic men, although this difference did not reach conventional levels of statistical significance. However, a significantly greater proportion of the hyperglycemic men than those who were normoglycemic fell into a higher ratio category when waist-to-hip ratios were classified according to whether they were less than or greater than or equal to 0.90. When the ratios were examined in relation to body mass index, the greatest difference between the two groups was observed in the leanest group. This study suggests that the waist-to-hip ratio, in conjunction with total body fatness, may be an important tool for distinguishing persons with hypertension who may develop hyperglycemia when treated with diuretics.

Adipose Tissue↗