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Biomedical subjects

L M Mirande

Publications and source records attributed to L M Mirande.

6 recordsLinked to original sources

[Early or malignant ulcerative syphilis. Considerations apropos of 2 cases. Bibliographic analysis].

Two cases of early ulcerative syphilis observed in the city of La Plata, Argentina, in the last 13 years are presented. Cases n.o 1, classified as Queyrat type, was in a previously bad general condition, due both to excessive smoking and alcoholism and showed a classic blood serologic test, that was slightly reactive. Case n.o 2, Milian type, presented a previously excellent general condition. The classic blood serologic test and FTAabs. were strongly reactive. It showed only a significant depression of cell immunity, with regard to the bacterial cutaneous proofs (bacterial skin-tests) carried out "in vivo". In both cases the clinical aspect was similar, with ulcerative necrotic lesions and affectation of the general condition which coincided with the outbreak of those lesions. The response to treatment was good, with rapid improvement of the general condition while the improvement of the skin lesions was slower and occurred only within 3 weeks.

Adult

[Furunculoid myiasis caused by Dermatobia hominis].

The authors report a case of forunculoid miasis by "Dermatobia hominis" ("Ura" fly). a process that being not very common in the Argentine Republic is sometimes misjudged as a furunculosis. The patient reported, a white woman, 51, travelled to a zone where this parasitose is endemid. After some time of her stay there, she noted three small nodes in her vulvar region. They grew on until reaching nearly the size of a walnut. At her first consultation with a gynecologist it was taken as a case of furuncolosis and treated with antibiotics. As the treatment didn't prove succesful, she asked for dermatological advice. It was then possible to verify the presence of three nodes. In the central hole of one of them, there could be seen a whitish body that soon disappeared inwards. This lead to the diagnosis of forunculoid miasis. An accurate and easy-to-perform treatment was carried out: a 1% solution of formaldehyde in distilled water was infused through the central hole of each node. This determined the larva's caudal extremity to appear in search of air. It was taken advantage of this situation to remove the larvae with a pair of nippers. "Dermatobia hominis" is widely spread in the warm-climated Argentine northern provinces of Chaco, Formosa and Misiones, as well as in Brazil, Paraguay and some regions of Uruguay. It is also known under the name of "Ura". It is a large fly, yellow faced, with dark-blue thorax; an almost rombic metallic-blue abdomen, orange antennae and legs, and dark-brown wings. It lives on the nutrients spared during its larval stage and both fecundation and oviposition, take place along its week-long life. The fecundated female catches different haematophagus insects on the wing, sticking sets of eggs to their abdomens. An embryo developes in each egg, being ready to emerge in a week but does this only when the bearer insect settles on a homeothermal being piercing and penetrating the skin of the new guest in about 10 minutes.

Diptera

[Topical use of the new corticoid difluocortolone valerate in dermatology].

The object of the present study was to investigate the clinical efficacy of Nerisona Fatty Ointment in very dry skin conditions. A total of 37 patients, most of them with chronic dermatoses, was treated. Either very good or good results were achieved in 83.8% of the cases. The side effects observed were very slight.

Adolescent

[ORF. Epidemiological, histopathological and clinical considerations, apropos of a case].

The observation belongs to a 22 year-old man, who presented a lesion in the index finger of the right hand, with a nodular induration, which later turned into an ulcer and was cured in a month and a half. In the beginning it was painless, becoming painful after the third week. He was given a treatment of a simple topical application. The histopathologic study showed the existence of an inflammatory chronic process with epidermic alterations characterised by the presence of necrosis and vesicles (reticular degeneration). There was also a significant presence of mural necrosis of vessels of the papillar dermis and subpapillar plexus, with recent partial mural thrombosis, that authors consider of importance in the pathogenic of the process. Comments are made about the evolution of the illness in man and in caprines and ovines. On enclose the histopathologic study of a biopsy of lip, extracted from a sheep affected by this illness. This showed a microscopic picture similar to the one described above.

Adult

[Variable pseudoerythroplasic telangiectasis balanitis].

This is a special case of balanitis, that authors separate from entities clinically established such as Erthroplasie of Queyrat, Balanitis of Zoon, Liquenoide Balantis with Plasmocytes and the Balantis of Sulsberger and Garbe's illness. The V. P. T. B. is clinically characterized by the presence of telangiectasies, ertroplasiform aspect, without any infiltration, non purpure, the V. P. T. B. goes through a first period truly esythematous and a second one in which these is also desquamation. That cycle is completed in a month. At the histopathologic level, the most important characteristics are: epidermis with its Malpighian layer in a normal state, the basal layers showing hidropic degeneration. The repper dermis shows a lichenoid picture that, in certain places affects the basal layer. The infiltrate is composed of: lymphocytes, monocytes and plasmocytes. Numerous telangiectasies are also observed.

Adult

[Epidermal peripilar nevus].

A classic case of Epidermal Nevus with a particular peripilar arrangement is presented. Histopathologically, acanthosis, hyperkeratosis and papillomatosis is observed. The indemnity of the hair appendages was demonstrated in three biopsies. Some observations are made about the classification of the epidermal nevus following recent research which includes epidermolytic hyperkeratosis and linear includes epidermolytic hyperkatosis and linear inflammatory nevus. Follicular and comedo nevus, which was included in the differential diagnosis of this patient, is discussed.

Adolescent