Biomedical subjects

L M Sádaba Echarri

Publications and source records attributed to L M Sádaba Echarri.

5 recordsLinked to original sources

PubMed2005

[Benign concentric annular macular dystrophy].

CLINICAL CASES: Two cases of benign concentric macular dystrophy are described. In one case, ophthalmologic examination, fluorescein angiogram and visual field measurement were performed. The presence of a juxtafoveal fibrosis in the other patient, indicate that choroidal neovascularization may be associated with this type of macular dystrophy. DISCUSSION: Benign concentric macular dystrophy is an entity with well-defined ophthalmoscopic and angiographic characteristics. Usually the prognosis is good. Rarely, choroidal neovascularization can be associated with this macular dystrophy.

Adult↗

PubMed2003

[Adult-onset foveomacular vitelliform dystrophy].

CLINIC CASES: Four cases of adult-onset foveomacular vitelliform dystrophy are shown. In two cases we were able to complete the exploration under optical coherence tomography. One of the patients developed spontaneous disappearance of the subfoveal deposit in her right eye along with an important decrease in her visual acuity. DISCUSSION: Adult-onset foveomacular vitelliform dystrophy is characterized by yellowish round-shaped bilateral, lesions in the subfoveal area. Optical coherence tomography reveal the presence of a slightly elevated lesion wich affects the retinal pigment epithelium and the external layers of neurosensory retina.

Adult↗

PubMed2003

[Prevalence and risk factors of pseudoexfoliation syndrome in institutionalized geriatric patients in Navarra].

PURPOSE: To establish the prevalence of pseudoexfoliation syndrome (PSX) in an institutionalized geriatric population in Navarra. To study the risk factors for the development of this disease. MATERIAL AND METHODS: 268 nursing home residents were studied, with a mean age of 81 years. The presence of PSX material in the anterior segment was best appreciated by slit lamp after pupillary dilation. We assessed its association with 13 ocular factors and 14 systemic factors. RESULTS: We found 10.1% (27) of subjects with PSX, 19 cases were unilateral and 8 bilateral. The frequency detected in subjects from Navarra was 7.9% versus 21.2% in subjects from other regions (p=0.02), although the significance was lost after multivariant logistic regression. The PSX was 3.5 times more frequent in patients suffering heart failure (p=0.01). The PSX was associated with anti-glaucomatous treatment, which multiplies the risk by 3.2 times (p=0.02); patients affected with age-related geographic macular atrophy had a 2.6 fold increased frequency (p=0.03), both after adjusting for age remained significant. We did not find any association between the PSX and other systemic factors (systemic hypertension and diabetes mellitus) or ocular factors (senile arc and cataract). CONCLUSIONS: The prevalence of PSX syndrome seems to be lower in an institutionalized population in Navarra than in other Spanish regions. The correlation with heart failure and age-related geographic macular atrophy suggests the possibility of a vascular role. The epidemiological association with increased IOP is confirmed.

Age Factors↗

PubMed2002

[Prevalence of drusen in homes for the elderly].

PURPOSE: To establish the prevalence of drusen in a population of over-65 year subjects residing in institutions. MATERIAL AND METHOD: A medical interview, ophthalmological examinations and midriatic retinography were performed in 392 older-than-65 year subjects living in homes for the elder (784 eyes). Each eye was reviewed by means of the Wissconsin Age-Related Maculopathy Grading System, in order to determine drusen frequency. RESULTS: Druses frequency totalled 33.3%. A great trend to symmetry was observed; bilateral in 23% of patients. The most frequent finding was multiple units (40 to 59 per eye), well defined soft drusen of 125 micrometer in size, which showed very little tendency to confluence. Twelve to 24% of macular area was affected by drusen. Subjects between ages of 65 to 74, presented the highest frequence. Drusen decreased with age from 75 years upwards. CONCLUSION: The observed drusen frequency found appear lower than those described in other studies outside our country, perhaps due to higher prevalence of media opacities. Midriatic retinography can be a good screening method for the detection of drusen.

Aged↗

PubMed2002

[Transpupillary thermotherapy in occult subretinal neovascularization in age-related macular degeneration. Preliminary results].

PURPOSE: To determine the efficacy of transpupillary thermotherapy (TTT) to treat choroidal neovascularization (CNV) in patients with age-related macular degeneration (ARMD). PATIENTS AND METHODS: Eight patients (ten eyes) with occult CNV were treated by TTT. A 810 nm diode laser was used to perform TTT. The diode laser was delivered through a panfunduscopic contact lens. RESULTS: Three eyes showed a visual acuity improvement and a decrease in exudation on fluorescein angiography. Four eyes remained stable. Nevertheless, lesions worsened after treatment in three cases. One of these cases suffered an overtreatment. CONCLUSIONS: TTT may be a useful therapy in some cases of CNV in patients with age-related macular degeneration. Randomized and multicentric studies are necessary to stablish precise indications of this therapy.

Aged↗