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Biomedical subjects

L M Shmuter

Publications and source records attributed to L M Shmuter.

At least 19 recordsLinked to original sources
PubMed1995

[Correlation between HLA antigens and immune status in dust-induced lung diseases in workers of machine-building industry].

Simultaneous study of immune state and HLA-testing was conducted for 73 patients with pneumoconiosis and 52 sufferers from dust bronchitis. The HLA antigens appeared to correlate with immune disorders in those diseases. The study revealed differences in the HLA antigens causing immune changes in pneumoconiosis and dust bronchitis. Those differences corresponded to differences between the markers of propensity to those diseases. Thus, the authors assume that formation of pneumoconiosis or dust bronchitis could depend on genetically determined variants of immune disorders.

B-Lymphocytes↗
PubMed1993

[Characteristics of the ambulatory care of patients with complicated forms of dust-induced bronchitis].

The efficacy of follow-up was evaluated in 83 patients facing complicated dust bronchitis of 2 and 3 grades. An active follow-up group was treated by immunopotentiators in clinic every 3-4 months so as to prevent recurrences, while the passive follow-up group received the stationary treatment only once a year. Observations within 3 years showed a great efficiency of the active follow-up combined with the antirecurrence treatment given 3-4 times a year. Immune status was stressed to improve in connection with the clinical relief.

Adjuvants, Immunologic↗
PubMed1993

[Immune reactivity in pneumoconiosis and coniotuberculosis in machine builders].

Immune status was examined in 231 patients facing pneumoconiosis and coniotuberculosis so as to observe a dependence on pneumoconiosis type (silicosis, electric welder's pneumoconiosis), severity of the process, activity of tuberculosis. Markedly changed T and B immunity, having already appeared at initial stage of the disease, were revealed. Those changes due to the tuberculosis activity were characterized by lymphocytosis, marked functional immaturity of T lymphocytes, depressed B lymphocytes count, elevated serum Ig level.

Adult↗
PubMed1991

[Use of chlotazol as an immunomodulating agent in chronic bronchitis].

A positive immunomodulatory effect was found in chronic bronchitis patients examined immunologically before and after treatment including chlotazol. T- and B-cell immunity recovered, clinical condition of the patients improved. A combination of known antimicrobial and antiinflammatory effects with an uncovered immunomodulatory one made chlotazol a valuable modality in the treatment of chronic bronchitis associated with secondary immune deficiency.

Adjuvants, Immunologic↗
PubMed1990

[Laser therapy in dust bronchitis].

Laser therapies of 43 dust bronchitis patients (4 cases in 1st stage and 39 cases in 2nd stage) were performed in comparison with routine therapeutic procedures of 28 patients (6 cases in 1st stage and 22 cases in 2nd stage). 14 acupuncture points were selected. A good therapeutic effect was attained in 16.3% sample group and 7.1% control group patients, satisfactory results--in respectively 58% and 42.9% cases, insignificant results--in 25.6% and 50% cases. Along with the favourable therapeutic effect, a positive influence of laser therapy on the immune system was established, particularly on the immunity T-system, in dust bronchitis cases. Laser therapy was recommended as part of complex treatment procedures for dust bronchitis patients.

Acupuncture Points↗
PubMed1976

[The relationship between the number of antibody forming cells in the spleens of rats immunized with Sal. typhi O-antigen and the number of background cells producing antibodies to that antigen].

It was shown on 5 series of rats by the method of local passive hemolysis in gel that the number of antibody-forming cells (AFC) in the spleen after the immunization with O-antigen from Sal. typhi correlated with the number of background AFC to the given antigen in the animals of the same series. This, possibly, pointed to the fact that the number of spontaneous AFC reflected the number of B-lymphocyte immunocompetent to the given antigen and could be used - to some extent - for the assessment of the immunological reactivity to this antigen before the immunization.

Animals↗
PubMed1975

Cyclic kinetics and mathematical expression of the primary immune response. Cyclic kinetics of antibody-forming cells following immunization with Salmonella typhi O-antigen.

The kinetics of antibody-forming cells (AFC) in the spleen of rats immunized with Salmonella typhi O-antigen was investigated. The number of nucleated cells of spleen and blood serum antibody titres in passive haemagglutination were determined in parallel. Cyclic changes in the number of antibody-forming cells were detected as three peaks on the 4th, 9th, and 13th days following immunization. The fluctuations of their number were not related to the total number of nucleated cells of spleen. The antibody titres reached their peak on the 10th day following immunization, decreased by the 14th day and rose again on the 16th day after immunization. Repeated increases of the number of AFC were probably due to the regular, not accidental, recruitment of committed precursors cells (memory cells).

Animals↗