PubMed Health⌕ Search

Biomedical subjects

L M Toporovskiĭ

Publications and source records attributed to L M Toporovskiĭ.

At least 19 recordsLinked to original sources
PubMed1990

[The rate of detecting Chlamydia in male homosexuals with syphilis].

A total of 159 homosexuals suffering from various forms of syphilis, aged 17 to 71, were screened for chlamydial antigen with the use of fluorescent monoclonal antibodies. Asymptomatic urogenital chlamydiosis was detected in 33 of 107 (30.8 percent) homosexual syphilitics. In 52 patients the material was collected simultaneously from the throat, urethra, and rectum; Chlamydia were detected in 71.2 percent of these.

Adolescent↗
PubMed1990

[Immunoenzyme analysis with capillary blood in the serodiagnosis of syphilis].

The technique of enzyme immunoassay with capillary blood was developed to be used in the diagnosis of syphilis. Analysis of the assay technique with blood serum and capillary blood from 170 syphilis patients and control subjects has shown a high sensitivity and specificity of the more convenient and simple procedure with capillary blood.

Antibodies, Bacterial↗
PubMed1990

[The combination of syphilis and HIV infection].

Seven cases of a combined course of syphilis ad HIV infection are described. All the patients are men, homo- and bisexuals. No apparent clinical features of syphilis in these patients were detectable. Recommendations on the strategy of syphilis treatment in patients with HIV infection are given.

AIDS Serodiagnosis↗
PubMed1990

[The immune status of homosexuals ill with different forms of syphilis].

Status of the cell-mediated, humoral immunity, and nonspecific defense factors were examined before and after specific therapy in 40 homosexuals suffering from secondary relapsing and latent early syphilis. The findings evidence that changes in the cell-mediated immunity of homosexual syphilitics essentially differ from those in heterosexuals with syphilis: decreased count of T-helpers and elevated one of T-suppressors evidence impaired ratio of T-lymphocyte subpopulations and immunoregulatory cell imbalance. A significantly increased level of C4 complement component was observed, evidencing a deficiency of the complement system. These data call for the development of a scheme of immunocorrective therapy for homosexuals suffering from syphilis.

Adolescent↗
PubMed1989

[A case of active tertiary syphilis].

A case of tertiary active syphilis in a 41-year-old male patient is described, who had not been administered specific treatment. Clinical symptoms of the disease manifested without apparent provoking factors; they were characterized by extensive involvement and no visceral abnormalities.

Adult↗
PubMed1989

[Characteristics of the course of latent forms of syphilis].

Seven patients with latent syphilis are described, in whom the routine serologic tests (RST) were negative during the first examination and over the course of therapy, and the specific tests (T. pallidum immobilization and immunofluorescence) were repeatedly positive before therapy. Early latent seropositive recurrent forms of syphilis were detected in the majority of these patients' sexual partners. The patients were not administered antisyphilis therapy before. The diagnosis of latent seronegative early syphilis negative in the RST is epidemiologically significant, for it helps timely carry out the necessary treatment and prophylaxis measures to prevent the disease dissemination.

Adult↗
PubMed1989

[Treatment efficacy in patients with secondary recurrent and latent early syphilis based on a new abbreviated method].

The authors analyze the findings of clinical and serological follow-up of 370 patients with secondary relapsing and early latent syphilis treated with a new rapid method. This method consists in intramuscular injections of water-soluble penicillin in high daily doses (4,000,000, 6,000,000, 8,000,000 U) made for 3-4 weeks. The follow-up period of 1-6 years has confirmed a high therapeutic efficacy of this method.

Diagnosis, Differential↗
PubMed1988

[Soft chancre].

Explore the source record for details and available documents.

Adult↗
PubMed1987

[Primary serological screening of the infection caused by the LAV/HTLV-III/HIV virus in Moscow].

The screening covering 5,155 residents of Moscow and 6,412 foreign students revealed the presence of antibodies to the virus, causing immunodeficiency in man, in 20 students from African countries. The antibodies were detected by means of the immune blotting assay. The problem of the possibility of the heterosexual transfer of the virus is discussed.

Acquired Immunodeficiency Syndrome↗