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Biomedical subjects

L Møller

Publications and source records attributed to L Møller.

30 records · Page 2Linked to original sources
PubMed1991

Social class and cardiovascular risk factors in Danish men.

During the last 25 years, a series of epidemiological studies in North-Western Europe and U.S.A. have demonstrated a negative association between social class and the incidence of cardiovascular disease (CVD), that is, an increasing incidence the lower the social class. In studies where possible explanations of this negative gradient have been analyzed, it was concluded that the traditional individual risk factors, such as elevated blood pressure, high serum cholesterol, and smoking, could explain about one half of the differences demonstrated. In a prospective study of a cohort of 504 men from the County of Copenhagen, the participants were examined when 40 and 51 years old. At both examinations the social class of the participants was recorded in addition to a number of cardiovascular risk factors. The latter included both the traditional risk factors and some not previously analyzed in relation to social class. At the 51-year examination we found statistically significant negative associations between social class and the following risk factors: plasma fibrinogen (p less than 0.001), short height (p less than 0.001), smoking (p less than 0.05), physical inactivity in leisure time (p less than 0.01), shift work (p less than 0.05), job strain (p less than 0.05), living alone (p less than 0.01), and having a poor social network (p less than 0.05). Two factors showed a significant opposite association with social class: Type A behaviour (p less than 0.001) and physical inactivity at work (p less than 0.001). In the last 10-15 years, a tendency has been demonstrated in many countries towards a strengthened association between social class and cardiovascular risk factors. This tendency was not found in our cohort. It has been discussed whether some of the social inequalities observed could be due to selection, so that people with a favourable cardiovascular risk profile socially were upward mobile. We found no support for such a selection hypothesis in our study.

Adult↗
PubMed1990

[Occurrence of passive smoking in Denmark].

The occurrence of passive smoking in the adult population in Denmark has not been described previously. This article publishes data from three investigations all of which were carried out in 1987. One was an interview investigation of a random section of the Danish population carried out by the Danish Institute for Statistics and Social Research (n = 1,464), the second was an investigation in Glostrup and the third was an investigation of employees in the Danish Customs and Excise (n = 3,775). Despite differences in the formulation of the questions and populations, the three investigations showed consistent results as regards the occurrence of passive smoking among adult Danes. About 12% of non-smokers were exposed to passive smoking for at least eight hours and 40% for at least one hour daily. Altogether 73% were exposed to passive smoking daily. About one third of the non-smokers were inconvenienced by passive smoking at work and a corresponding fraction had taken steps to reduce the extent of passive smoking in their daily life.

Cohort Studies↗
PubMed1984

Cerebral ventricular size in the offspring of schizophrenic mothers. A preliminary study.

Within a prospective, longitudinal study of offspring of schizophrenic mothers, computed tomographic scan-derived measurements of ventricular size were evaluated for a subsample consisting of schizophrenics, borderline schizophrenics (DSM-III schizotypal), and mentally healthy individuals. Schizophrenics exhibited larger ventricular sizes and borderline schizophrenics smaller ventricular sizes than mentally healthy individuals. Ventricular size correlated with premorbidly obtained obstetric data. These results are interpreted as being consistent with the hypothesis that neurological insult may decompensate schizotypal individuals toward florid schizophrenia.

Adolescent↗
PubMed1979

Alcohol-induced brain damage and liver damage in young males.

37 alcoholic males under the age of 35 were examined clinically, by psychometric tests, by computerised tomography (CT scans), and by liver biopsy. Factors other than alcoholism that might have caused brain damage were excluded. The prevalence of brain damage in this group was far greater than that of severe liver damage: 59% were intellectually impaired and 49% had cerebral atrophy on CT scan, whereas only 19% had cirrhosis. There was no significant correlations between the degree of liver damage and the degree of intellectual impairment (p greater than 0-05), nor between the degree of intellectual impairment and the presence of cerebral atrophy. The CT scan is an inadequate measure of functional brain damage, psychometric testing is preferable. Other neurological complications of alcoholism were not impressive. Disabling intellectual impairment may be the earliest complication of chronic alcoholism and may arise early in the alcoholic career.

Adult↗
PubMedDate not supplied

Plasma fibrinogen and ischemic heart disease risk factors.

The association between risk factors for ischemic heart disease and plasma fibrinogen level was analyzed in a cross-sectional population study. All 51-year-old men living in a certain area within the county of Copenhagen were invited; 439 of 542 (81%) participated in the study. Data were collected via questionnaire and at health examinations. The following independent variables were analyzed: social variables, which included social class, marital status, and job strain; psychological and psychosomatic variables, which included abdominal pain, personal and economic problems, self-assessed state of health, and degree of loneliness; behavioral variables, which included smoking, drug consumption, physical activity, use of sugar, and alcohol consumption; and physiological variables, which included high density lipoprotein (HDL) and low density lipoprotein (LDL) cholesterol, physical fitness, fasting glucose level, waist-to-hip ratio, and systolic blood pressure. In the multivariate analyses, the following variables showed an independent positive association with plasma fibrinogen level: one social variable (low social class); two psychological variables (abdominal pain index and personal/economic problems); two behavioral variables (smoking and physical inactivity during leisure time); and three physiological variables (low HDL cholesterol, low physical fitness, and high LDL cholesterol). The strongest independent associations with plasma fibrinogen level were found for smoking, social class, LDL cholesterol, and HDL cholesterol. These analyses suggest that smoking is a major risk factor for an elevated plasma fibrinogen level, but that other factors such as social class, cholesterol level, physical inactivity/physical fitness, and psychological problems also influence plasma fibrinogen level.

Abdominal Pain↗