HIV-1 isolation and p24-antigen detection in cerebrospinal fluid of subjects with neurological abnormalities related to AIDS.
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Biomedical subjects
Publications and source records attributed to L Majori.
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Thirty patients with congestive cardiomyopathy (C.C.) have been studied for the prevalence of neutralizing antibodies to coxsackie B viruses in comparison with age and sex matched controls. Seropositivity toward each antigen was similar in cases and controls: an exception was coxsackie B5 virus, where a significantly seropositivity was found in the control group. As a whole, high antibody titers to any antigen were observed more frequently on sera of cardiopathic patients; however the difference between cases and controls of g.m.t. to each antigen tested was not statistically significant, with the exception of coxsackie B1 virus. The absence of a clear relationship between C.C. and viral infections might be explained through biological as well as epidemiological considerations; of particular relevance, the long duration of cardiac disease (average length 71 months, median 54). Final considerations are offered regarding the methodologic approach for a better understanding of the etiology of this elusive disease.
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This report concerns 3 cases of human listeriosis occurred in the area of Trieste between 1974-1979. Two newborns with a listeric early disease were observed in a Neonatal Intensive Care Unit. One child was colonized during the delivery from the infected vaginal mucosa of the mother; no signs of sepsis nor systemic involvement was observed. In the second case a bacteremia was documented with clinical signs of sepsis, and in spite of negative cultures of the mother, an intra-uterine infection was hypothesized. During an investigation carried out in 1977 on prevalence of listeric infection in pregnant women of Trieste, 127 vaginal and rectal swabs were examined and one subject (0.8%) was found harbouring a strain of Listeria monocytogenes in the vaginal secretions. Some bacteriological and epidemiological topics on human listeriosis are discussed.
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