PubMed HealthSearch

Biomedical subjects

L Martín

Publications and source records attributed to L Martín.

At least 19 recordsLinked to original sources

Acquired symmetric lipomatosis of the soles. A plantar form of the Madelung-Launois-Bensaude syndrome.

Benign symmetric acquired lipomatosis is a rare condition characterized by multiple, diffuse, subcutaneous collections of nonencapsulated mature adipose tissue. A thick and disfiguring deposit of fat is symmetrically distributed in the subcutaneous tissue of the neck, upper trunk and proximal portions of the upper extremities. The face, distal extremities, hands, and feet are characteristically spared. We describe a case in which only plantar involvement was present.

Adipose Tissue

[The prediction of the severity of acute pancreatitis by C-reactive protein].

Reactive C Protein (RCP) has been determined in fifty-one patients with acute pancreatitis. RCP has been compared with Ranson's criteria which include several clinical and biochemical parameters. The value of 20 mg/dl is the one which discriminates serious acute pancreatitis from the mild forms in a 84.3% of patients. Sensitivity and specificity of RCP and Ranson's criteria are compared, the results obtained are similar (88.9% vs. 81.8% and 94.4% vs. 97%). In summary, the determination of RCP is very useful for its simplicity and accuracy in the prognosis of acute pancreatitis.

Acute Disease

Postlymphography linear dermatitis.

Cutaneous effects secondary to lymphography are rare events. We herein report a patient with Hodgkin's disease who developed a linear dermatitis in both lower limbs 6 days after a pedal lymphography. Histopathologic examination of the lesions demonstrated a subacute dermatitis. Patch tests with the substances used in the lymphography yielded negative results. We discuss the possible pathogenic mechanisms of this striking linear dermatitis.

Adult

Linear pemphigus vulgaris along a surgical scar.

A 64-year-old female had breast carcinoma of the right breast, and a mastectomy was performed. Three years later she developed a vesiculobullous eruption along the surgical scar. Histopathological and direct immunofluorescence findings were consistent with a diagnosis of pemphigus vulgaris. We discuss the possible pathogenesis for this striking linear distribution of the pemphigus vulgaris lesions.

Breast Neoplasms

Erythema elevatum diutinum in a patient with acquired immunodeficiency syndrome. Another clinical simulator of Kaposi's sarcoma.

Several types of vasculitis have been described in patients with human immunodeficiency virus infection. Erythema elevatum diutinum is a rare variant of cutaneous leukocytoclastic vasculitis which, with the exception of the case reported herein, has been described only once in human immunodeficiency virus-infected patients. Our male patient, a longtime intravenous drug abuser, had cutaneous lesions, closely resembling Kaposi's sarcoma, on the extensor surfaces of the lower extremities. Cutaneous biopsy specimens, however, demonstrated leukocytoclastic vasculitis with fibrinoid necrosis of the vessel walls and areas of basophilic degeneration of collagen bundles in early lesions, whereas late lesions showed dense diffuse fibrosis with proliferation of dermal spindle cells and some foci of residual leukocytoclastic vasculitis. Oral therapy with dapsone resulted in marked clearing of the cutaneous lesions within few days. This case raises the necessity of histologic confirmation for all cases of suspected Kaposi's sarcoma in patients with acquired immunodeficiency syndrome. We discuss the possible pathogenesis of leukocytoclastic vasculitis in human immunodeficiency virus-infected patients.

Acquired Immunodeficiency Syndrome

Localized hyperkeratosis lenticularis perstans (Flegel's disease).

A case of hyperkeratosis lenticularis perstans involving only the back of a thirty-nine-year-old woman is reported. Histologic examination showed foci of compact and eosinophilic hyperkeratosis overlying a thinned stratum malpighii. In the underlying papillary dermis there was no evidence of inflammatory infiltrate. This case demonstrates that hyperkeratosis lenticularis perstans may appear as a localized disorder, and that the inflammation is not an essential pathogenic process in this disorder.

Adult

[Cutaneous epithelial necrosis in coma. Study of 2 cases].

We report two cases of epithelial necrosis in comatous patients. The cutaneous lesions were characterized by erythematous plaques which later evolved to bullous lesions. Histologic examination demonstrated epidermal necrosis with subepidermal blisters, sparse neutrophilic inflammatory infiltrate and, characteristically, eosinophilic necrosis of the eccrine sweat gland coils.

Adult

[Endoscopic retrograde cholangiopancreatography (ERCP) in pediatric surgery].

We present four pediatric patients with biliary pathology in which endoscopic retrograde cholangiopancreatography (ERCP) was obtained in order to achieve a more complete diagnostic work-up. Although ERCP is not presently a routine diagnostic technique in children, in this report we evaluate the additional advantages, indications and drawbacks of this technique, especially in the planning for the surgical repair of the biliary pathology.

Child

[Percutaneous cholecystostomy guided by ultrasonography. A preliminary experience].

Surgical cholecystostomy is a palliative treatment for cholecystitis and distal biliary obstructions when the general condition of the patient does not allow complex techniques. Percutaneous cholecystostomy (PC) guided by ultrasonography is an alternative to that procedure as well as a method of direct access to the biliary tract for diagnostic examinations (bacteriologic study of bile and percutaneous cholangiography). During one year, 9 female patients, mean age 74 (49 to 90) underwent this approach; 5 patients had cholecystitis, 2 were suspicious of biliary sepsis and 2 had angiocholitis. Because of poor general condition, no other approach was possible in any of the cases. There were no relevant complications. All 5 cases of cholecystitis improved after the procedure although 3 patients died within 30 days of causes unrelated to PC. In two cases biliary sepsis was ruled, and the probe was withdrawn, without complications. The two patients with angiocholitis improved significantly; in both cases it was shown that the cause was cholelithiasis: later on, they were treated by different methods (endoscopic sphincterotomy in one case and surgery in the third case). These preliminary results suggest that PC guided by echography should be included as a routine therapeutic and diagnostic method in the management of digestive diseases.

Aged

[Crohn disease in 3 siblings].

Three siblings without a known familiar history of chronic inflammatory disease of the intestine suffered Crohn's disease. They were the 3rd, 4th and 8th siblings of a family of 8 siblings. The onset of the disease and its course were similar in all three patients. Considering the form of familial presentation and the possible influence of environmental factors in this type of patients, a review is made of the influence of these factors in accordance with the clinical patients' evolution.

Adult

[Anomaly of the biliopancreatic junction, choledocal cyst and pancreatic lithiasis. Endoscopic possibilities].

Choledocus cyst is a rare anomaly which affects the intramural segment of the common bile duct. The presenting clinical symptoms are recurrent abdominal pain, episodes of jaundice, with fever, and increased levels of serum amylase. Although the diagnosis may be obtained by conventional clinical and radiologic methods, the anatomy of the ducts is best demonstrated by endoscopic retrograde cholangiopancreatography; moreover, this technique enables some therapeutic manoeuvres. We present a young girl with a choledocus cyst and some other ductal abnormalities with the results of the previously mentioned technique.

Calculi