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Biomedical subjects

L Martindale

Publications and source records attributed to L Martindale.

18 recordsLinked to original sources

Electron microscopy of the juxtaglomerular apparatus in young fowl fed a salt deficient diet.

Kidneys from young fowl fed a salt deficient diet for up to five weeks were examined under the electron microscope. The presence of maculae densae (MD) were confirmed and the concentrations of nuclei in the MD and the remainder of the distal convoluted tubules were compared. In the proximal convoluted tubules, salt deprivation caused mitochondrial changes, an increase in intranuclear and cytoplasmic lipid and the deposition of urates. Regional thickening of the glomerular basement membrane was observed in many kidneys. In the normal kidney, there is an age dependent increase in the juxtaglomerular granules in the cortical glomeruli (P less than 0.02), but not in the juxtamedullary glomeruli. In salt deprived birds, juxtaglomerular granules were increased in the juxtamedullary glomeruli (P less than 0.01) but not in the cortical glomeruli. Salt deprivation also caused a significant reduction in bodyweight after five weeks (P less than 0.002) and increases in heterophil (P less than 0.02) and monocyte (P less than 0.05) counts in the blood.

Animals↗

Attitudes of women and men physicians.

Attitudinal data obtained from interviewing random samples of women and men physicians in metropolitan Detroit indicated that women were generally more liberal and egalitarian than men. Older women were more liberal/egalitarian than older men while younger men were closer in attitudes to younger women. Within specialities, women and men physicians frequently held similar attitudinal scores; however, controlling for age, sex accounted for more variation than did specialty. A weighted combination of variables which together most significantly discriminated between age and sex subgroups pointed to a sensitivity dimension. This was stronger in the women; yet men demonstrating a similar sensitivity were found in almost every age and specialty grouping. Although younger men physicians are less conservative than older men physicians, both younger and older women physicians demonstrated strong liberalism/egalitarianism.

Adult↗

Deep pectoral myopathy: an experimental simulation in the fowl.

Surgical occlusion of the subclavian artery of domestic fowls has been found to induce a condition closely resembling, in location and histopathology, the deep pectoral myopathy of turkeys. The operative procedure is described and the significance of the collateral blood supply in the pathogenesis of the lesion is briefly discussed.

Animals↗

Comparison of the productivity of women and men physicians.

Data obtained from random samples of 87 women and 95 men physicians in the Detroit metropolitan area indicate that, at the time of surgery, 84% of the women and 96% of the men were engaged in medical work. Only 7% of the women were not working because of reasons related to the traditional female role. Fifty-nine percent of the women and 87% of the men had worked full-time since medical school graduation. Fifty-one percent of the women, compared to 39% of the men were in primary care specialties. Since medical graduation, women physicians spent 90% as much time in medical work as did the men, despite the fact that most of the women had full responsibility for homes and families.

Efficiency↗

Renal function changes in laying hens fed on dried poultry manure.

1. Renal function was studied in laying hens which had been fed on diets containing 0 (controls), 10 or 20% dried poultry manure (DPM) for one year. 2. Birds fed on 20% DPM showed increased rates of effective renal plasma flow and increased renal tubular secretion of urate during the infusion of large amounts of urate. 3. Renal hypertrophy was not detected in any group.

Aminohippuric Acids↗

The fate of recycled urate in hens fed on a diet containing dried poultry manure.

1. Seven colostomised hens were fed on a control diet free of dried poultry manure (DPM) or one including 20% DPM. 2. Urate excretion was greater during DPM feeding by approximately the amount consumed: little urate was present in faeces. 3. Doses of 10-6 muCi of 14C-urate introduced into the crop were quantitatively excreted in the urine within 24 h. 4. The results show that none of the urate present in DPM is utilised by the laying hen.

Animal Feed↗

The effect of high dietary sodium chloride on renal function in chicks.

1. One-day-old male broiler chicks were fed on diets containing 3-8% or 2-7% added NaCl in two experiments lasting 22 and 42 d respectively. 2. Sodium clearance was increased in treated birds in both experiments. No other changes in renal function were observed but an increase in plasma urate in treated birds of the first experiment may indicate some loss of proximal tubular function. 3. Renal function, relative to body weight, diminished slowly with age in control and treated birds but these changes could not be related to the fact that at about 3 weeks of age testicular cysts no longer develop.

Animals↗

Phosphate excretion in the laying hen (Gallus domesticus).

1. The excretion of phosphate during the calcifying and non-calcifying phases of egg formation was studied.2. The pattern of phosphate excretion was observed during increasing body loads of phosphate.3. A tubular mechanism for phosphate excretion is proposed in which tubular phosphate secretion occurs proximal to, or coincidental with reabsorption.4. Parathyroid extract increased the rate of phosphate excretion and appeared to inhibit both the reabsorptive and secretory mechanisms.5. The pattern of excretion of phosphate loads by hens in the calcifying phase was closely similar to that of birds in the non-calcifying phase when treated with parathyroid extract.6. The relationship between shell calcification and the parathyroids is discussed.

Absorption↗

The relation between skeletal and extracellular-fluid magnesium in vitro.

1. Femora from control and magnesium-deficient rats were incubated in media of different magnesium concentrations. 2. Magnesium was lost at the same rate from fresh and boiled bones to a magnesium-free medium. 3. The equilibrium established was dependent on the magnesium concentrations in both the bone and the medium. 4. Parathyroid extract increased the rate of magnesium loss from bone to a magnesium-low medium containing bovine serum (50%), but had no effect in a protein-free medium.

Journal Article↗

Nursing faculty's knowledge and attitudes toward persons with AIDS.

The research examined knowledge, fear, homophobia, and the willingness to care for persons with AIDS. The subjects were 45 faculty members from nursing programs in a mid-southern state. The study was an extension of an earlier study by Lester and Beard (1988). A 56-item questionnaire consisting of knowledge and attitude questions was used. Attitude questions were categorized into fear, homophobia, and the intent to give care. With the level of significance set at (p less than .01), homophobia and fear were significantly correlated positively. Knowledge was not significantly correlated with any of the variables. Findings suggest that AIDS education should be directed toward changing attitudes and values by promoting learning in the affective domain.

Acquired Immunodeficiency Syndrome↗