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L Marzo

Publications and source records attributed to L Marzo.

12 recordsLinked to original sources

Popliteal artery entrapment syndrome: the role of early diagnosis and treatment.

BACKGROUND: The purpose of this study was to evaluate whether certain factors could influence arterial impairment at presentation for treatment of popliteal artery entrapment syndrome (PAES) and whether its early diagnosis could optimize long-term results. METHODS: Between 1979 and 1995, 30 patients were treated for PAES at our institution. Patients were characterized by age, risk factors, associated diseases, preoperative symptoms, affected side, dominant limb, duration of symptoms, musculotendinous structure causing the compression, arteriographic findings, arterial status at presentation, type of operation, postoperative complications, and long-term follow-up. RESULTS: Twenty-nine (65%) limbs underwent musculotendinous section (MTS), 15 (33%) limbs underwent vascular reconstruction, and 1 (2%) was surgically explored. Patients submitted to MTS were younger (mean, 31 +/- 3 years) than patients who underwent vascular reconstruction (mean, 41 +/- 4 years; p < 0.05). MTS limbs had a greater number of minor symptoms compared with those that underwent vascular reconstruction (62% versus 20%; p < 0.02). Arteriogram showed that MTS limbs had a greater number of normal findings at rest when compared with limbs that underwent conventional reconstruction (85% versus 0%; p < 0.001). No specific factors influenced the arterial status at presentation. During follow-up, treadmill examination revealed that MTS limbs had a better response (96%) than limbs that had undergone vascular procedures (67%; p < 0.02). MTS limbs had a better long-term patency rate (mean, 87 +/- 7 months) compared with limbs that were submitted to vascular reconstruction (mean, 107 +/- 8 months) (95% versus 65%; p < 0.02). CONCLUSIONS: Because PAES is a progressive disease that can create serious vascular obstructive disease and no specific factors seem to influence the degree of vascular impairment, the detection and treatment of PAES at an early stage permit better long-term results.

Adolescent↗

[Importance of the pre-donation epidemiological survey to detect donors with a risk of transmitting HCV].

PURPOSE: To determine if the investigation of previous clinical features through an inquiry could be useful to predict HCV infection in blood donors as assessed by recombinant immunoblot assay. MATERIAL AND METHODS: From january 1990 to august 1991, 79 HCV seropositive blood donors by recombinant immunoblot assays (58 RIBA 1 and 21 RIBA II) were selected to be inquired and to perform a clinical examination. The inquiry included the following parameters: age, sex, social environment, history of liver disease, presence or absence for parenteral risk factors (surgery, blood transfusion, odontological procedures, acupuncture, tattoos, etc...). RESULTS: 1) General data: mean age, 43 years (range 20-65); male/female 54/25 (ratio 2.16); urban/rural environment 50/29 (ratio 1.72); new/regular blood donors 17/62 (ratio 0.27). 2) Inquiry results: In seven cases (8.9%) previous symptoms were detected. Hepatic stigmata were present in 12 donors (15.2%). A 67.0 showed previous surgical procedures; 48.1% had odontological history; 24.0% were recipients for blood transfusion; parenteral treatment using nondisposable material were detected in 19 cases (24.0%); acupuncture in 4 donors (5.0%); tattoos in only one case. Social habits were: alcoholic consumption in 44.3% and regular medicine ingestion in 19.0%; a 81.0% had a unique partner and a 8.9% preferred multiple heterosexual contacts. A 29.1% inhabit in unfamiliar house and the remaining 70.9% lived in apartments buildings; the mean of family members was 3.7 persons (range 2-8). REMARKS: a) It is pointed out the scarce and physical expression of the HCV infection. So in many aspects the inquiry is useless and time consuming. b) Nevertheless, we have detected some parenteral risk factors in seropositive cases. Regarding this particular aspect the inquiry is useful. Taken into account the previous we suggest to add an item with the parenteral risk factors to the ordinary self-answering inquire, addressed to all blood donors in each donation.

Adult↗

[Incidence of anti-HCV and ALT in blood donors].

A study was carried out in 2,000 blood donors aimed to assess the incidence of anti-C hepatitis virus antibodies. Of the total number of samples, 10 cases were found positive (0.5%), a figure lower than the national average. Of these 10 cases, ALT levels were high in 5 (0.2%). The potential risk of post-transfusion C hepatitis increases in accordance with the number of blood units transfused. This incidence of anti-C hepatitis virus antibodies is discussed with regard to previous findings in other countries, the incidence of positive donors being also very low.

Alanine Transaminase↗

[Familial childhood cortical hyperostosis].

We present three cases of Caffey's disease, which have been observed in a family and a previous one former generation of the same family. A review of the literature upon family cases is carried out (35 families with 143 patients) prevailing the hypothesis of the type of autosomal dominant trait with incomplete penetrance and variable expressivity. HLA system is studied in such a family without common haplotypes being found and therefore the trait does not seem to be linked to genes of this system.

Female↗