Biomedical subjects
Publications and source records attributed to L Marzuoli.
We report our functional results about 81 ossiculoplastys during tympanoplasty with closed technique in chronic cholesteatomatous otitis. We discuss our functional results and the post-operative assessment of the audiometric gain. Patients presented either cholesteatomatous otitis sequelea or any preliminary status (retraction pockets) with attical impairment.
Among the hidden parts of the middle ear, the posterior part of the atrium undoubtedly raises the most interest of otologists. The attic is a frequent localization of cholesteatoma and retraction pouches. Its anatomy is not well known, especially the anterior and internal walls. This anatomic study, based on the dissection of 41 petrus bones was designed to determine the anatomic limits and describe the "noble structures" of this region in order to "guide" future surgical procedures.
We report a new case of primary atypical carcinoid of the larynx. This rare neuro-endocrine neoplasm of the larynx was initially mis diagnosed in 50% of the cases published. Since, characteristically these are lesions of the epilarynx causing dysphonia at early stages of development, the diagnosis should be kept in mind when the work-up for dysphonia reveals a small tumor of the epiglottis or aryepiglottic folds. The histological diagnosis should be oriented by Grimelius staining and confirmed immunoperoxidase marker studies for chromogranin and cytokeratin. Although, atypical carcinoids of the larynx are aggressive malignant tumors, the prognosis for early lesions of less than 1 cm is excellent. However, unlike early squamous cell carcinomas, these tumors do not respond well to radiation therapy. Primary surgery is the treatment of choice.