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Biomedical subjects

L Masłowski

Publications and source records attributed to L Masłowski.

7 recordsLinked to original sources

[Lipoprotein and plasminogen serum levels in patients with diabetes mellitus type 2: risk factors for macroangiopathy? Preliminary study].

Lipoprotein(a) [Lp(a)] is the specific lipoprotein which physiological role has not been explained. Similarity between apolipoprotein(a) and plasminogen structure suggests, that Lp(a) can be the bridge connecting the lipid metabolism and the coagulation system. The aim of the study was to evaluate if there is any correlation between Lp(a) and plasminogen serum concentrations in patients with diabetes t.2. 20 males and females with diabetes t.2 in the age 19-75 years (mean: 54.9 years). The control group consisted of 15 healthy men and woman in the age of 23 years (medical students). Lp(a) was estimated by ELISA, plasminogen by turbidimetric methods. Lp(a) serum level in the examined group was: 40.06 + 59.45 mg%. In 7 patients it was over 30 mg%. In the control group: Lp(a) concentration was: 13.23 + 10.5 mg%, no one was above 30 mg%. The different was significant. Plasminogen concentration was: in patients: 94.08 + 53.08%, in the control group: 89.08 + 40.7%. There was no significant difference. Correlation index between Lp(a) and plasminogen concentrations was in the patient's group: 0.3, in the control group: 0.2. In patients with diabetes we can find increased Lp(a) commentation in serum and normal plasminogen concentration. Concentration of Lp(a) didn't demonstrate significant correlation with plasminogen serum level.

Adult↗

[Neutrophil elastase activity in patients with ulcerative colitis].

In order to find an objective marker of disease intensity, neutrophil elastase activity was determined in patients with ulcerative colitis. The study included 41 patients with ulcerative colitis who were divided into two groups depending on tge stage of the disease on the basis of the activity index according to Maier et al. The obtained results of studies were compared a group of 18 healthy persons. The values of neutrophil elastase activity in the patients and in the control group were subjected to statistical analysis. It was found that neutrophil elastase activity in the patients with high degree of disease intensity was lower than that in the patients with low degree of disease intensity and in healthy subjects. The obtained differences were statistically significant. From the results of the study the conclusion was drawn that the neutrophil elastase activity may be an indicator of ulcerative colitis activity.

Adolescent↗

[Evaluation of arterial supply to the legs by noninvasive methods in elderly patients with diabetes].

Rheographic investigations and segmental measurements of pressure by Doppler method were done in 49 patients with type II diabetes or with impaired glucose tolerance who had chronic ischaemia of lower extremities in all stages, after Fontaine. The diagnostic usefulness of both methods was demonstrated, similarly as the correlation of their results with clinically determined progression of arterial ischaemia of the lower extremities. Parallel application of both methods was particularly useful in diabetic since it made possible detection of Mönckeberg's arteriosclerosis and evaluation of collateral circulation development.

Aged↗