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Biomedical subjects

L McCain

Publications and source records attributed to L McCain.

15 recordsLinked to original sources
PubMed1992

Making a difference in the breast implant issue.

The Food and Drug Administration's (FDA's) investigation into the safety of silicone gel-filled breast implants has dominated newspaper, television, and magazine headlines across the country in recent months. ASPRSN member Lynne McCain along with several patients and physicians from the Atlanta, GA area recently had an opportunity to educate lawmakers and staff on the issue of breast implants while on Capitol Hill in October. They later returned to testify before an FDA panel investigating the issue and played a key role in the panel's November decision to recommend keeping the implants on the market until further research was available on the safety of the implants. The following article details the group's efforts with lawmakers in October and before FDA panel members in November, and demonstrates that nurses and patients can make a difference!

Expert Testimony↗
PubMed1992

Counseling the woman with silicone breast implants.

Public interest in silicone breast implants has heightened in recent months due to increased media hype that has included unscientific reviews and exaggerated accounts of a few women's problems. Lynne McCain, BSN, RN, of Emory Clinic's Section of Plastic and Reconstructive Surgery in Atlanta, provides common questions asked by patients with breast implants followed by appropriate responses that could be given in counseling.

Counseling↗
PubMed1992

Breast imaging and the augmented breast.

Women with augmented breast implants are presenting for mammograms in greater numbers over the past year due to recent publicity regarding the safety of silicone gel-filled implants. New issues are being raised in light of this recent increase, making it essential for patients and health care providers to understand the limitations of mammography and how to best minimize problems.

Adult↗
PubMed1991

Specular microscopy studies on the corneal endothelium after cessation of contact lens wear.

We performed specular microscopy on the corneal endothelium of 22 long-term hard contact lens wearers (15-32 years duration) and 22 age- and sex-matched controls. We found polymegethism in users as shown by a significant difference in the coefficient of variation in cell area (p less than 0.01) and pleomorphism as shown by a significant decrease in the percent of 6-sided cells (hexagonality, p less than 0.01). There was no significant difference in cell density and mean cell area between the 2 groups. Contact lens wear was discontinued in five eyes of three patients after they were entered into the study and switched to eye-glasses. Specular micrographs were taken up to 60 months after discontinuation of use of the lenses. Comparison of the above parameters before and after discontinuation of the lenses did not show a significant change. However, there was a trend toward improvement in the coefficient of variation in the eyes that were followed the longest. This finding suggests that the morphological changes induced by long-term use of contact lenses may be slowly reversible after prolonged discontinuation of contact lens wear.

Adult↗
PubMed1987

A comparative study between the PAM and the laser interferometer in cataracts.

We conducted a prospective study on 35 consecutive eyes undergoing cataract extraction to compare the Guyton-Minkowski Potential Acuity Meter (PAM) and the Laser Interferometer (LI) in determining potential visual acuity. The eyes were divided into: group A, which had good visualization of optic disc details, and group B, whose media allowed only disc outline or less to be seen. We found that in group A eyes, both instruments were reliable (with accuracies of 94% for the PAM and 88% for the LI). However, in group B eyes (advanced cataracts), both instruments were unreliable (accuracies of 33% for the PAM and 53% for the LI). Interestingly, in a subgroup of high myopes (axial length greater than 29 mm) with moderate cataracts and poor visual acuties, both instruments were very reliable and helpful in determining how much of the vision loss was due to the cataracts. We therefore strongly recommend potential acuity testing in high myopes with moderate cataracts and poor visual acuity.

Aged↗
PubMed1985

Correlation of ocular rigidity and blue sclerae in osteogenesis imperfecta.

A previous study of 16 patients and 16 controls had indicated that the mean ocular rigidity value was significantly lower in Osteogenesis Imperfecta (OI) patients than in normal controls (p = 0.001). These preliminary results have been confirmed in the present study of 46 patients and 53 controls where the difference in mean ocular rigidity between the patient and control group was statistically significant at the p less than 0.0001 level. Of particular interest was the inverse correlation between blueness of sclera and ocular rigidity in patients with OI. The establishment of such a relationship depended upon the availability of a larger sample size than had previously been examined.

Adolescent↗
PubMed1983

The contralateral eye in the iridocorneal endothelial (ICE) syndrome.

Examination of six cases of iridocorneal endothelial (ICE) syndrome revealed that all the patients had subclinical abnormalities in the fellow eye. Of the six, four patients had iris transillumination, four patients had significantly decreased outflow facility but without elevation of intraocular pressure, and all patients had corneal endothelial changes as noted by specular microscopy. The asymmetric rather than unilateral involvement and the similar histopathology to posterior polymorphous dystrophy suggested that these two diseases may share a common pathogenesis. The occurrence of features of Rieger's syndrome and Axenfeld's anomaly in association with posterior polymorphous dystrophy suggested the hypothesis that all these diseases may be characterized by abnormalities of tissues derived from neural crest cells. A unifying hypothesis is presented to explain this group of diseases involving the endothelial cells lining the anterior chamber, namely corneal and trabecular meshwork endothelium, anterior iris stroma and iris melanophores.

Adult↗
PubMed1983

Asymmetric pigment dispersion syndrome.

The hypothesis proposed by Campbell goes a long way to clarify the loss of pigment from the posterior iris pigment epithelium in PDS. However, the present series of cases of either asymmetric PDS (cases 1 to 3) or early developing PDS (cases 5 to 7) suggest that other factors appear to play a role in addition to mechanical rubbing. These other factors await further identification.

Adolescent↗
PubMed1981

Low ocular rigidity in patients with osteogenesis imperfecta.

Sixteen patients with osteogenesis imperfecta (OI) have undergone a thorough eye examination. These patients had statistically significantly lower ocular rigidity measurements than a group of normal volunteers matched on age, sex, and refractive error. In addition, the corneal diameter and length of the eyeball was smaller in OI patients than that in controls. Possible correlations of low ocular rigidity with biochemical changes in scleral collagen await further investigation.

Adolescent↗