PubMed Health⌕ Search

Biomedical subjects

L Mikkelsen

Publications and source records attributed to L Mikkelsen.

29 records · Page 2Linked to original sources
PubMed1977

A simplified model for teaching minor oral surgery.

A teaching model, specially constructed for the purpose of training senior dental students in the use of surgical instruments, is described. The advantages of this model are inexpensiveness and reproducible simulated surgical situations securing a uniform teaching objective.

Education, Dental↗
PubMed1977

A comparison of four commonly used local analgesics.

In a double-blind, cross-over, clinical study with nine probands, the efficiency parameters of four commonly used local analgesics were evaluated: 2% Carbocain with adrenaline 1:200,000, 3% Citanest with Octapressin 0.03 iu/mul, 3% Carbocain Dental, and 2% Xylocain with adrenaline 1:80,000. It was found that 3% Carbocain Dental (no vasoconstrictor content) demonstrated significantly shorter duration of analgesia than the other solutions in the soft tissues as well as in the dental pulp. 3% Citanest with Octapressin exhibited the longest soft tissue duration, but as far as duration of tooth analgesia was concerned there was no significant difference between 3% Carbocain Dental and 2% Carbocain with adrenaline. The longest duration of tooth analgesia was shown with 2% Xylocain with adrenaline; this solution also possessed the highest frequency of analgesia and extent of analgesia. All probands personally preferred injections with 3% Carbocain Dental as injection with this solution resulted in the least discomfort.

Adult↗
PubMedDate not supplied

IgA1 proteases of oral streptococci: ecological aspects.

The ecology and identity of IgA1 protease-producing streptococci in the human oral cavity were studied in an attempt to obtain insight into the significance of IgA1 proteases for host-parasite relationships. Contrary to previous observations, a detailed taxonomic analysis of oral streptococci revealed that all strains of S. sanguis and S. oralis ("S.mitior") produced IgA1 protease. In addition, IgA1 protease activity was observed in some isolates of S.mitis. Of the streptococci that initiate plaque formation on dental enamel 88% (median value) had IgA1 protease activity. Low proportions of the streptococci that colonize the tongue and oropharyngeal mucosae produced IgA1 protease, in contrast to 60% of streptococci isolated from buccal mucosa. The IgA1 proteases from S. sanguis I-III, S. sanguis IV, S. oralis, and S.mitis were distinct as revealed by studies using enzyme-neutralizing antibodies.

Adult↗