PubMed Health⌕ Search

Biomedical subjects

L Miti

Publications and source records attributed to L Miti.

36 records · Page 2Linked to original sources
PubMedDate not supplied

[The coagulation picture and plasma clearance capacity in atherosclerotic diabetics].

An attempt is made to set out the complex question of the relations between plasma and wall factors in coagulation, platelets and lipids in atheroscderotic diabetes. The literature data show that this disease is associated the clotting and fibrinolytic systems as a result of the prevalence of thrombogenic factors and/or poor inhibitor activity. A survey is made of fibrinolysis activators and inhibitors, and of the part played by lipids in the aetiopathogenesis of thrombophilia, though the mechanisms responsible have not yet been fully established. Reference is made to De Gaetano's exposition of Walsh's views concerning the rôle of platelets in clotting. An assessment is made of the relations between platelets and lipoproteins, and hence of the importance of platelets in the pathogenesis of atherosclerosis. Reference is made to a series of atherosclerotic diabetics. Hyperaggregability was noted in 60% of 30 cases. The experimental results obtained by Bierman et al. on the relation between insulin and lipoproteinlipase and the interference of insulin with PHLA are presented in an explanation of the clarifying power of plasma in this disease. Lastly, an account is given of lipoproteinlipase values observed in a personal series of 48 cases employing a radioimmunological technique. Baselines were depressed in 24 subjects.

Aged↗
PubMedDate not supplied

[Incidence of coronary, cerebral and lower-limb atherosclerosis in diabetics].

The literature data regarding the incidence of coronary, cerebral and lower extremity atherosclerosis in diabetes are reviewed. A retrospective assessment of data relating to in-patients of the Umberto I Hospital Medical Division during 1972-1975 showed that atherosclerosis occurs more often and earlier in diabetics. It is more frequent in women over 50, especially in the case of coronary forms. A similar high incidence of vascular lesions is also noted in subclinical forms. This is particularly true of coronary sites in females and lower extremity sites in males. It is clear that screening for glucose intolerance in all vasculopathic subjects, coupled with careful genetic and familial investigation, are essential acids to preventive and social medicine in this particular sector.

Adult↗