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Biomedical subjects

L Mo-Suwan

Publications and source records attributed to L Mo-Suwan.

14 recordsLinked to original sources
PubMed1997

Calcium and phosphate solubility curves for parenteral nutrient solutions containing Vaminolact.

Calcium and phosphate incompatibility in the total parenteral nutrient (TPN) solutions is a common problem especially in neonates. Their combinations in TPN admixture must be tested before use. We here investigated the compatibility of calcium and phosphate in TPN solutions containing a newborn amino acid product, Vaminolact. The TPN test-solutions contained 10 per cent dextrose, 1, 2, or 3 per cent Vaminolact, 4 mmole/L of magnesium sulphate and various combinations of calcium gluconate and dipotassium phosphate. Precipitations and crystallizations were inspected visually and microscopically after 24 hours standing at room temperature. Solubility curves were made by plotting the maximum concentrations of calcium and phosphate at which both were still compatible in the solution. Such curves are extremely helpful for clinicians and pharmacists to administer maximum calcium and phosphate dose for individual patient requirement.

Amino Acids, Essential↗
PubMed1996

Risk factors for cardiovascular disease in obese and normal school children: association of insulin with other cardiovascular risk factors.

OBJECTIVE: To investigate the level of insulin and other known cardiovascular risk factors in school children and their association with obesity. DESIGN: Cross-sectional study. SUBJECTS: 123 normal and 116 obese school children categorized by weight-for-height, mean age: 10.2 and 10.5 years old respectively. MEASUREMENTS: Family histories of diseases by questionnaires; blood pressure (BP) and waist and hip circumferences by measurements; fasting blood for glucose, insulin, total cholesterol, HDL-cholesterol and triglycerides. RESULTS: The numbers of boys in the normal and obese group were 65 and 58, those of the girls, 53 and 63 respectively. The obese group was more likely to have family histories of obesity, high blood pressure and diabetes; had significantly greater waist-hip-ratio (WHR), higher systolic and diastolic BP, lower HDL-cholesterol, higher triglyceride and fasting insulin levels (with fasting blood sugar in the normal range) than the normal weight group. In a crude analysis, insulin levels were positively correlated with obesity, systolic BP, WHR, age and triglycerides and negatively associated with male gender and HDL-cholesterol. After adjustment using multiple regression, only obesity status, age, gender and triglycerides still remained significantly associated with insulin level. Limitation of utilizing family disease history report for identification of children at risk was discussed. CONCLUSION: These findings suggest that risk to coronary heart disease and hypertension through insulin resistance already operates in school-aged children.

Analysis of Variance↗
PubMed1996

Impacts of training of village health volunteers in reduction of morbidity from acute respiratory infections in childhood in southern Thailand.

In 1990, the Ministry of Public Health of Thailand started a five-year education program on management of cases with acute respiratory infection (ARI). The objective of this-study was to test whether such a program could reduce the average number of sick days of the target children. 30 villages in the study district were randomly allocated into 15 study and 15 control villages. A 2-day training workshop for village health volunteers from the study villages was conducted. The cohort of children age below 5 years in the two areas were followed-up for 19 week in the peak season of the disease. Among the 664 and 649 target children with 67,083 and 67,984 child-days observed in the study and the control villages, 71 and 41 children, respectively, were free from any episode. The preventive odds ratio of treatment adjusted for age and village effects = 0.88, 95% (CI 0.4-1.95). The median of the average sick periods in the individuals were 27 and 34 days, respectively. After adjusting for age, episodes/month and locality, the ratio of average sick days between children in the study and control villages was 0.89 (95% CI 0.76-1.05) or 11% shorter duration without statistical significance. The adjusted odds ratios of visiting the health center, private clinics, the community hospital and provincial hospital were 0.95 (95% CI 0.69-1.25), 1.43 (95% CI 0.98-2.11), 2.01 (95% CI 1.06-3.82) and 4.71 (95% CI 1.50-14.8), respectively. The training program thus had rather little impact on morbidity of the disease but tended to promote utilization of higher level of health services by the affected children.

Acute Disease↗
PubMed1995

Goiter in Thai schoolchildren: study in Hat Yai, southern Thailand.

Examination for goiter was performed in 6,035 schoolchildren (2,899 girls, 3,136 boys), aged 8-17 years, from primary and secondary schools in Hat-Yai municipality, Songkhla province. Goiter was detected in 355 children (combined prevalence 6%; 232 or 8% in girls, 123 or 4% in boys). Of the 355 children with goiter, 214 (60%; 148 girls, 66 boys) participated in the study, and had blood drawn for free thyroxine (FT4), triiodothyronine (T3), thyroid stimulating hormone (TSH), and thyroid antibodies. All had urine collected for iodine excretion. The diagnoses of goiter were as follows: simple goiter in 192 (89.8%; 129 girls, 63 boys); juvenile autoimmune thyroiditis in 18 (8.4%; 16 girls, 2 boys); Graves' disease in 2 girls (0.9%); thyroid adenoma in 1 boy (0.45%), and ectopic thyroid in 1 girl (0.45%). Acquired hypothyroidism was found in 4 out of 18 children with juvenile autoimmune thyroiditis (22.2%). Iodine deficiency disorder was not evident in children examined shown by high urinary iodine excretion of more than 50 mcg/gm creatinine (mean 298, range 70-630). In conclusion, simple goiter is a common occurrence in children and adolescents in Southern Thailand. Juvenile autoimmune thyroiditis should be identified and differentiated from simple goiter as it is the most common cause of acquired hypothyroidism. Iodine deficiency is not evident in Southern Thailand, at least in the urban areas of a large city.

Adolescent↗
PubMed1993

Calcium and phosphate solubility curves for parenteral nutrient solutions containing aminoplasmal-paed, Aminovenos-N-pad or Moripron-F.

We investigated the calcium and phosphate compatibility in three amino acid products: Aminoplasmal-paed, Aminovenos-N-pad, Moripron-F. The final TPN sample solution contained 10 per cent dextrose, 1-3 per cent amino acids, 4 mmol/L magnesium sulphate and various combinations of calcium gluconate and dipotassium phosphate. Precipitates and crystallization were inspected visually and microscopically after 24 hrs standing at room temperature. Calcium-phosphate solubility curve were drawn. Among the three amino acid products, Moripron-F gave the highest buffer capacity. These curves are extremely helpful to predict the compatibility of a calcium-phosphate dose in the TPN solution using these three amino acid products.

Calcium↗
PubMed1991

Breast-feeding and infant growth in the first six months.

Weight and length of 67 breast-fed infants were followed every two weeks from birth to 6 months. All infants were healthy and developed normally. Weight curves were found to be parallel to the NCHS and Bangkok curves up to 4 months then bending slightly but not statistically significant. This supports "the breast-fed infants having a different growth pattern from the mixed (breast-formula) fed" finding observed in studies from developed countries. In comparison to the NCHS and Bangkok length data, rural male infants were significantly (p less than 0.01 and 0.05 respectively) shorter from birth onwards, whereas, median lengths of the rural female infants were significantly shorter (p less than 0.01 and 0.05 respectively) after 4 months. Genetic influence on linear growth was thought to be the cause. The cautious use of the current growth curves on breast-fed infants was emphasized.

Body Height↗
PubMed1990

Transitional society, health status and international migration of Muslim villagers in the lower part of southern Thailand.

A survey was carried out in a Malay-speaking Muslim community in southern Thailand to obtain baseline data for planning of long term multidisciplinary research and development. By using a 30-cluster sampling technique, 210 households of 1,308 subjects were studied in the post-Ramadan period. It was found that the community was in a social transition. The crude birth rate was 4% and 37.6% of the households had at least one migrant. About half of these migrants had been to Malaysia and mainly worked in rubber plantations. Ninety-five per cent of the households had electricity whereas only 23.8% had a latrine. Boiled or rain water was regularly drunk in only 13.3 per cent of the households. Home-grown agricultural products were not sufficient to provide adequate food. Twenty-six per cent of the adults were unemployed and 24.6% were illiterate. Of the pregnancies 26.7% had no antenatal care and complete tetanus toxoid was given to only 27.8%. Traditional birth attendants conducted 81.1% of the deliveries and only 28.9 and 24.4% of the umbilical cords were correctly cut and correctly dressed, respectively. Breast feeding was still a common (87.8%) practice. However, complete immunization was given to only 10.8%, and 37.8% of the infants had at least one diarrheal episode in the previous month. It was concluded that high birth rate, high migration, low education, low income and bad health of infants are major problems. These problems were interlinked and needed a special multidisciplinary approach. In addition to common obstacles for routine health delivery, migration may create international complications, particularly related to maternal and child care.

Adolescent↗
PubMed1990

TSH secreting pituitary adenoma in children: a case report.

The clinical presentation of TSH-secreting pituitary adenoma in an 11-year-old boy is reported. Hyperthyroidism, signs and symptoms of increased intracranial pressure with the elevation of TSH, T3, T4 were the clues for suspecting this disorder. Bilateral carotid angiogram was performed which disclosed a suprasellar mass, and pituitary surgery was performed. Electron microscopic examination confirmed the diagnosis of TSH secreting pituitary tumor.

Adenoma↗
PubMed1989

Predictors of low birthweight delivery: a study of factors influencing birthweights.

The average birth weight among the 292 infants was 3,028 (+/- 349 g). The incidence of LWB was 8.9 per cent, being predominantly SGA. There were no significant statistical differences of socioeconomic, obstetric and anthropometric variables between the mothers of the LBW and non LBW groups. Maternal height and mid arm circumference seem to be a promising predictors of LBW delivery. The decision of the cut-off points of these variables depends on the objective and the available resources. These variables should be field-tested in a wider scale before being advocated for use as predictors of LBW delivery.

Adult↗
PubMed1979

Clinical profile of diarrhoea at Ramathibodi Hospital during 1977.

Restrospective clinical profile of diarrhoeal disease in children admitted to the Pediatric Department, Ramathibodi Hospital during January to December 1977 was studied. A total of 144 medical records (55.6%) could be analysed; Rectal swab culture yielded enteropathogenic organisms in 47.2% of the cases consisting of 26.3% Salmonella, 16.0% sero typing positive E. coli and 3.5% Shigella. Clinical presentation of each group was presented which with the exception of neurological symptoms was in concordant with previous observations of several authors. Convulsion was more frequent in the Salmonella group, although dehydration and frebuency of stools were less severe. These cases seem to be highly infectious and tend to be more chronic with recurrences. It could be seen in all age group. Shigella was seen in infants 6 months old and older. Isolation of Rota-virus was not done, in none specific diarrhoeal groups (52.8%) many of which might have been due to Rota-virus. White blood count and differential count were of little value in differential diagnosis of the aetiology. Stool examination was helpful especially in Shigellosis and E. coli but there were no characteristic findings in Salmonella and non-specific groups. The overall mortality rate was 4.1%.

Child↗