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Biomedical subjects

L Mosca

Publications and source records attributed to L Mosca.

At least 91 records · Page 5Linked to original sources

Plasma and tissue distribution of adriamycin in patients with pelvic cancer.

The levels of adriamycin in plasma, ascitic fluid and normal and neoplastic tissues sampled during surgery of 3 patients with advanced pelvic cancer were measured by fluorimetry. The highest content of fluorescent compounds was found in tumoral masses in necrotic or scarcely viable tissue; viable and invasive tumor areas scored fluorescence levels comparable with normal adnexa. Ascitic fluid contained levels of fluorescence comparable to the last observed phase of plasma levels. Adipose and cutaneous tissue scored the lowest concentrations.

Aged↗

Saccular aneurysm of infancy and early childhood: report of a case.

A case of intracranial saccular aneurysm with intracerebral haematoma occurring in early childhood and presenting with sudden loss of consciousness and right hemiparesis is reported. The aneurysm was located in the opercular portion of the left middle cerebral artery. Surgery, besides removing the intracerebral haematoma, involved clipping and complete removal of the aneurysmal sac. The child made an uneventful recovery, and he is completely safe after 40 months. Microscopic examination of the lesion shows disruption of the normal sequence of the original layers, with widespread inflammatory cells.

Angiography↗

The Empty Sella syndrome secondary to Rathke's cleft cyst.

A case of Empty Sella secondary to Rathke's cleft cyst, successfully operated on, is reported. Asymptomatic cysts of Rathke's pouch are fairly frequent autopsy observations. They can cause optic-chiasmatic and endocrine symptomatology or, very rarely, an Empty Sella syndrome if the cyst is very large.

Craniopharyngioma↗

Immunopathology and microvascular lesions in human sympathetic ganglia.

Lumbar sympathetic ganglia surgically removed from adult patients affected by obstructive peripheral arteriopathies are investigated with traditional histology and fluorescent antibody technique. The presence of various pictures of microangiopathy is confirmed, mainly haemodynamic (hyaline-oedematous perivascular thickening) phenomena. Since specific fluorescence is absent from any lesion, the autoimmune pathogenic hypothesis may be discarded.

Adult↗