[Antibiotics and allergy].
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Biomedical subjects
Publications and source records attributed to L Mosonyi.
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The main features of interrelations between different organ systems are described and their possible role in therapeutic aims discussed. In the question on the connection of immunoallergic phenomena and vegetative nervous system the authors' standpoint on their mutual interrelation is stressed. The most important characters of the immunoallergic organ system are studied and its correlations with the female hormonal factors interpreted; further therapeutic trials in this aspect seem to be justified. The problem of mutual stimulation between certain organ systems' functions is likewise dealt with.
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The immunodeficiency, at present an important complex of research, can be classified in 4 main groups. Primary forms can be separated from secondary ones, a third group of interactional type from a fourth one of compensatory character. We suggest a new classification based on a common point of view, which avoids terms as "common variable immunodeficiency" and allows corrections by the results of further research.
1. Decreases of serum calcium concentration in dogs lead to increased basal tone of Oddi's sphincter in the employed experimental model. 2. This effect is independent of the agent used for decreasing the serum calcium level. 3. Spasmolysis was observed immediately after the injection of CaCl2. CaCl2 alone, however, had no effect in "normocalcaemic" animals. 4. Local decrease of calcium level plays no significant role in the sphincter spasm. It is suggested that the spasm is elicited by increased smooth muscle excitability as a consequence of the hypocalcaemic state prevailing in the body.
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Four cases with clinical and biochemical evidence of hyperparathyroidism are reported. The syndrome was due to DHT-intoxication of iatrogenic origin in the first case to histologically confirmed C-cell hyperplasia of the thyroid in the three others. The collective term "regulatory hyperparathyroidism" is porposed for the syndromes which, in distinction to secondary parathyroidisms, have a pathogenesis other than a negative calcium balance. Management of the syndrome is discussed with particular emphasis on the removal of the TCT-producing hyperplasia or adenoma, and the restoration of the electrolyte balance.
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