[Complete anomalous outlet of the pulmonary veins not associated with other cardiac malformations (isolated form). Study of 30 confirmed cases].
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Adolescent↗
Biomedical subjects
L Muñoz
Publications and source records attributed to L Muñoz.
[Ontogeny of cardiac antigens in chickens].
The embryonic development of the heart is a complex process in which molecular events take place during the cellular recognition, growth regulation and morphogenesis. In this work, the stage in which cardiac antigens are produced in the chick embryo was established by the use of sera directed against cockerel's heart antigens. Chick embryos were studied in different stages of development, classified according to the Hamburger and Hamilton system. Soluble and insoluble fraction of the cockerel's heart were obtained and used to immunize rabbits; the presence of anti-heart antibodies was tested by double microimmunodiffusion. Antisera to yolk and albumin envelopment, serum and cockerel erythocytes were also produced in order to recognize other molecules in the embryos. Anticockerel red cells antibodies were determined by direct hemaglutination. It was shown that heart antigens appear since the second stage of embryonic development and remain during the whole development, although in some stages it seems that the concentration of some antigens decreases. It is possible that the molecular changes in the heart tissue are manifested as variations in concentration of the cardiac substances.
Albumins↗
[Double outlet of the right ventricle with anterior aorta to the left of the pulmonary artery in situs solitus].
Two cases of double outlet of the right ventricle with an anterior aorta to the left of the pulmonary artery are described. Both in situs solitus. One had an anterior interventricular communication, and other had a middle posterior communication. The importance of the aortic component of the second sound is analyzed with regard to its localization and intensity. An analysis is also made of the morphology of the cardiac silhouette and the peculiarities of the electrocardiogram as diagnostic aides in the malformation. Considerations are made of the distinct theories which explain the malformation. It is clearly shown that a correct diagnosis is necessary since this cardiopathy may be treated surgically.
Abnormalities, Multiple↗
[Double outlet chamber from the right ventricle with restrictive interventricular communication].
We report two cases with double outlet right ventricle and subaortic restrictive ventricular septal defect. Both had atrial situs solitus and atrioventricular concordance. There were no other associated defects. Both cases were diagnosed by means of an angiocardiographic study and case two was also studied anatomically. Additional data for the diagnosis were findings of left ventricular overload by the EKG; left atrial enlargement and signs of venocapillary hypertension by the chest X-rays; left ventricular/right ventricular pressure gradient by the hemodynamic study and the angiographic findings. One case had mitro-aortic discontinuity. Case two had a double infundibulum, being the left one the responsible for the restrictive ventricular septal defect. We conclude that double-outlet right ventricle with restrictive ventricular septal defect cases have their own clinical, hemodynamic and angiographic features which have to be accurately studied in order to offer an adequate surgical treatment.
Aorta, Thoracic↗
[Isolated hypoplasia of the right ventricle].
Four cases of hypoplastic right ventricle with intact ventricular septum are presented. All of them were diagnosed by means of an angiographic study, and one case was examined postmortem. The anatomic, physiologic and clinical features of this malformation are analyzed and the differential diagnosis with similar congenital cardiac diseases is discussed.
Adolescent↗