PubMed Health⌕ Search

Biomedical subjects

L N Briantseva

Publications and source records attributed to L N Briantseva.

6 recordsLinked to original sources
PubMed1984

[Experience with the restorative treatment of locomotor injuries at an outpatient rehabilitation center].

The article analyzes the experience with the treatment of 960 trauma patients in the restoration department of the out-patient clinic and makes an assessment of some organizational and clinical aspects of its activities. High percentage of favorable results (95,9%) was shown by late follow-up of the patients after injuries. Bad results were found in 4,1% of cases, 5,4% of the patients had temporary invalidism. A conclusion is made that the efficiency of the treatment in the restoration department may be improved by eliminating some problems of organizational character.

Absenteeism↗
PubMed1984

[Prevention of the formation of drug resistance in bacterial populations by using biologically active substances].

The patients with infected wounds of the extremities were treated with kanamycin electrophoresis in combination with chlorhexidine bigluconate, an antiseptic. As compared to the patients treated with kanamycin alone, the rate of the wound size decrease in such patients was 2 times higher. The levels of microbial contamination in these patients were much lower. The contamination level with the aerobic flora was 4.8 times lower, including staphylococci, the level of contamination with which was 5.9 times lower. The contamination level with the kanamycin-resistant bacteria was 22 times lower. The treatment with kanamycin alone resulted in a 2.6-fold increase in the number of the antibiotic-resistant variants in the microbial populations of the wounds. In 48.2 per cent of the patients, this was accompanied by development of resistance to kanamycin in the whole microbial population of the wound. The development of the kanamycin resistance in the staphylococcal populations of 18.1 per cent of the patients was associated with changed sensitivity of the initial strains and in 81.9 per cent of the patients, with superinfection by the resistant strains. No changes in the kanamycin sensitivity of the initial gram-negative organisms during the treatment were observed. The use of chlorhexidine bigluconate, as a biologically active substance in combination with kanamycin potentiated the action of the antibiotic, prevented development and accumulation of the antibiotic-resistant variants in the microbial populations of the wounds and development of the drug resistance in these populations.

Bacteria↗