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L N Gerchikov

Publications and source records attributed to L N Gerchikov.

10 recordsLinked to original sources
PubMedDate not supplied

[Toxicological characteristics of the Soviet antidepressant pyrazidol].

It has been demonstrated in different species of experimental animals (mice, rats, cats, dogs) that the Soviet drug pyrazidol is a little toxic drug. Prolonged repeated administration of pyrazidol does not exert any damaging action on the vitally important organs and systems of the body. Pyrazidol is less toxic than imipramine.

Animals↗
PubMedDate not supplied

[Toxicological study of the Soviet tetracyclic antidepressant inkazan].

The toxicology of an original Soviet antidepressant inkasan-3-methyl-8-methoxy-3H, 1,2,5,6-tetrahydropyrazino [1,2,3-ab] beta-carboline hydrochloride was studied in different types of experimental animals (mice, rats, rabbits, dogs). It was established that the drug is less toxic than imipramine. The toxic manifestations (seizures, stereotypy) seen in dogs receiving high doses of inkasan for a long time are likely to be linked with a stimulating component that characterizes the drug action on the central nervous system.

Animals↗