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Biomedical subjects

L N Mutanda

Publications and source records attributed to L N Mutanda.

At least 37 records · Page 2Linked to original sources
PubMed1980

Epidemiology of acute gastroenteritis in early childhood in Kenya: aetiological agents.

In a case-control study of 36 infants and children admitted to Kenyatta National Hospital with acute gastroenteritis and an equal number of age and sex-matched controls, rotavirus was found to be the major aetiological agents; 39% of the 36 children had evidence of rotavirus infection as opposed to 2 (6%) in controls. Six Shigella species were isolated from the test group and none from the control. No significant difference was found between children with diarrhoea and controls wth regard to frequency of isolation of enteropathogenic and enterotoxigenic E. coli, Salmonella species and enteroviruses. Mixed infections occurred between rotaviruses and other enteropathogens. None of the 17 serum pairs obtained from children with diarrhoea showed a significant titre rise to complement-fixing adenovirus group antigen.

Acute Disease↗
PubMed1972

Agglutination of African primate and rodent erythrocytes by adenoviruses, reoviruses, and enteroviruses.

African nonhuman primate and rodent erythrocytes were tested for agglutination by adenoviruses, reoviruses, and enteroviruses. Squirrel erythrocytes were agglutinated by reovirus serotypes and adenovirus types 3, 11, 16, and 21. Adenoviruses also agglutinated brazza monkey erythrocytes to the same titers as those obtained with either rhesus or grey monkey cells. Prototype reovirus types 1 and 2 agglutinated grey monkey erythrocytes to much lower titers than either squirrel or human group O red cells. Among the enteroviruses tested, only echovirus types 7 and 12 agglutinated grey, red-tail, brazza, and rhesus monkey erythrocytes. The specificity of agglutination of squirrel, grey, and brazza monkey erythrocytes by reoviruses, echoviruses, and adenoviruses, respectively, was confirmed by hemagglutination-inhibition tests. The titers obtained were similar to those obtained with erythrocytes usually used in these tests. Erythrocytes of bush babies, potto unstriped grass mice, swamp rat, rusty-nosed rat, bush rat, harsh-furred mice, soft-furred rat, and giant rat were not agglutinated by adenoviruses, reoviruses, or enteroviruses.

Adenoviridae↗