[Main results of studies in area 06. "AIDS"].
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Biomedical subjects
Publications and source records attributed to L N Reshetnikova.
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A scheme for isolation of highly purified type F Cl. botulinum toxin has been developed. The scheme allows one to obtain the toxin with specific activity of 1.5--4.0 X 10(7) Dlm/mg protein, molecular weight of 150,000 daltons, a typical protein UV spectrum and the optical density ratio E280/E260 = 1.98.
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Toxins extracted from the cells and the culture fluid of C1. butulinum type E had a similar mol wt and antigenic composition. Trypsin activation led to the appearance of an additional antigen. Coefficient of the cell toxin activation was much greater than the coefficient of activation of the toxin contained in the culture fluid.
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