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Biomedical subjects

L Nobile

Publications and source records attributed to L Nobile.

27 records · Page 2Linked to original sources

PubMed1982

Azidofibrate. Synthesis and evaluation of its effects on fat cell lipolysis in vitro.

Synthesis and biological properties of a new ethyl alpha-(p-chlorophenoxy)-isobutyrate (clofibrate) analogue are described. Replacement of the chlorine atom of the parent drug by an azido group has been attempted in order to avoid the proliferative action on liver peroxysomes. The new compound showed a good degree of inhibition of rat fat cell lipolysis and its action, qualitatively different from that of clofibrate, bears some analogy with that of nicotinic acid.

Animals↗

PubMed1972

[Synthesis of bis-homoanalogues of nucleosides].

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Magnetic Resonance Spectroscopy↗

PubMedDate not supplied

[Analysis of fetal maturity by amniotic fluid].

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Amniotic Fluid↗

PubMedDate not supplied

[Neural tube defects. I. Prenatal diagnosis].

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Acetylcholinesterase↗

PubMedDate not supplied

[Clinical and obstetrical indications for cesarean section in a teaching hospital, Jundiaí (SP)].

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Brazil↗

PubMedDate not supplied

[Clinical examination of fetal vitality].

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Female↗

PubMedDate not supplied

[Down's syndrome. I--Considerations on maternal variables].

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Adolescent↗

PubMedDate not supplied

[Down's syndrome. II--Considerations on conceptual variables].

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Abnormalities, Multiple↗

PubMedDate not supplied

Extractive spectroscopic insulin determination in pharmaceutical formulations.

Two methods are proposed, one spectrophotometric and one spectrofluorimetric, for the determination of insulin in several pharmaceutical formulations. The methods were found to be fairly simple, sensitive and accurate, and thus suitable for this purpose. Both methods involve an extractive step with diethyl ether for the elimination of excipient interference, and subsequent direct spectrometric analysis. Spectrophotometric determinations were carried out at lambda = 276 nm; spectrofluorimetric determinations were carried out at lambda em = 306 nm with lambda exc = 277 nm.

Amino Acid Sequence↗