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Biomedical subjects

L Noonan

Publications and source records attributed to L Noonan.

7 recordsLinked to original sources

Freshwater submersion injuries in children: a retrospective review of seventy-five hospitalized patients.

OBJECTIVE: To determine whether or not selected victims of submersion accidents can be safely managed as outpatients. DESIGN: Retrospective chart review. SETTING: Children's Medical Center of Dallas. PATIENTS: One hundred forty-eight charts reviewed, comprising all hospital admissions after submersion accidents from April 1987 to April 1994. RESULTS: Of the 148 patient charts that were reviewed, 73 patients were excluded from the study for the following criteria: endotracheal intubation before initial medical evaluation; transfer form an inpatient unit of another medical facility; history of preexisting neurologic, neurodevelopmental, and/or pulmonary disease. Of the 75 evaluable patients, 3 were directly admitted to the inpatient service with no documented initial medical evaluation reported in the medical record. Of the remaining 72 patients, 62 (86%) were symptomatic at the time of the initial medical evaluation in the emergency department; 10 patients (14%) were asymptomatic. Seventy percent of the initially asymptomatic patients and 57% of patients who were symptomatic at the time of initial medical evaluation were asymptomatic by 8 hours after the submersion event. By 18 hours postsubmersion, all patients who were initially asymptomatic and 72% of initially symptomatic patients were normal. Thirty-five percent and 80% of patients who had abnormal initial physical examinations and abnormal chest x-rays had a normal physical examination by 8 hours and 18 hours, respectively, and all remained normal. CONCLUSIONS: Routine hospital admission of all children who have had immersion accidents is unnecessary.

Adolescent↗

Invasive cervical cancer and depot-medroxyprogesterone acetate. WHO Collaborative Study of Neoplasia and Steroid Contraceptives.

Preliminary results of a study of the possible relationship of depot-medroxy-progesterone acetate (DMPA) to invasive cervical cancer are presented. The findings are based on data from three participating centres in Thailand and one in Mexico. A relative risk for cervical cancer of 1.2 was observed in women who had ever used DMPA; this was not statistically significant. No consistent increase in risk with duration of use was observed, although a relative risk of 2 was found in women who had used DMPA for more than 5 years. This observed increase in risk was confined to women who were aged under 46 years or who had first been exposed to DMPA before 30 years of age. These findings are based on small numbers of subjects, and may not represent a causal relationship.

Contraceptive Agents, Female↗

Breast cancer and depot-medroxyprogesterone acetate. WHO Collaborative Study of Neoplasia and Steroid Contraceptives.

The preliminary results of a study of the incidence of breast cancer in relation to use of depot-medroxyprogesterone acetate (DMPA) are presented. The findings are based on data from three participating centres in Thailand, and one each in Kenya and Mexico. A relative risk for breast cancer of 0.7 was observed in women who had ever used DMPA; this was not statistically significant. Although no consistent decrease in risk with duration of use was observed, the lowest relative risk (0.5) was observed in women who had used DMPA for three or more years. These findings are based on small numbers and must be considered preliminary. However, they provide no evidence that DMPA increases the risk of breast cancer, and suggest that it may exert a protective effect, particularly in long-term users.

Breast Neoplasms↗

Five seasons of sadness.

In response to her grandmother's death, moving back to her family, and beginning kindergarten, Bridget experienced a very difficult adjustment. During the period of play therapy, she began grief work: "Emancipation from bondage to the deceased, readjustment ot the environment in which the deceased is missing, and formation of new relationships."15 Bridget, at the age of five, has experienced five seasons of sadness. Yet her quiet and determined strength has enabled her to readjust to her once threatening environment. The therapist suggested continued therapy in the school environment to aid Bridget in formation of new relationships. The shadow of Bridget's five seasons of sadness seems to have lifted. Her bright affect and look of expectancy seem to be asking of the other children: "Will you be my friend? For no reason that I know Except I want you so."16

Affective Symptoms↗