Post-transplant lymphoproliferative disorder with Hodgkin's lymphoma and large B-cell lymphoma differentiation.
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Adult↗
Biomedical subjects
L Novoa-Takara
Publications and source records attributed to L Novoa-Takara.
Lymphocytic hypophysitis in a man presenting with hypercalcemia.
A 59-year-old man with a 30-year history of type 2 diabetes mellitus presented with fatigue, confusion, and weight loss over a 3-month period. He was found to be hypercalcemic (11.8 mg/dL) and dehydrated, and his hypercalcemia improved with intravenous fluids. While in the hospital, he developed hyponatremia, hypoglycemia, and hypotension. He was found to have a subnormal cortisol level of 2.3 microg/dL at baseline, which increased to only 5.6 microg/dL 60 minutes after a 250-microg corticotropin intravenous stimulation test. The patient developed pneumonia and adult respiratory distress syndrome and died of an acute myocardial infarction. During the autopsy, he was found to have lymphocytic hypophysitis with a severe reduction in corticotropin-producing anterior pituitary cells. No malignancy was identified at autopsy. He is the first male patient to be described in the literature who presented with hypercalcemia caused by lymphocytic hypophysitis.
Autopsy↗
Premature "closing" of the foramen ovale in transposition of the great arteries with intact ventricular septum: rare cause of sudden neonatal death.
We report a male neonate who developed severe cyanosis and bradycardia at birth unresponsive to resuscitation. At autopsy he was found to have premature "closure" of the foramen ovale together with transposition of the great arteries and an intact ventricular septum. Reviewing the literature, we found only one case report describing a similar neonate with this lethal combination of cardiac malformations.
Fatal Outcome↗