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Biomedical subjects

L Orte

Publications and source records attributed to L Orte.

At least 55 records · Page 3Linked to original sources

Hypertension in primary chronic glomerulonephritis: analysis of 288 biopsied patients.

The prevalence of hypertension in 288 patients with primary chronic glomerulonephritis was compared with that observed in a control group of 3,477 subjects from the same geographic area. 23.3% of the patients and 12.8% of the general population were hypertensive (p less than 0.01). However, if only patients with normal renal function were considered, prevalence of hypertension (12.7%) was not higher than in the control group. Hypertension was more frequent in focal segmental sclerosis (30%) and in membranous glomerulonephritis (26%) than in IgA nephropathy (9%), membranoproliferative glomerulonephritis (11%) and IgM mesangial glomerulonephritis (12%). Five years after renal biopsy, 92% of normotensive and 47% of hypertensive patients remained with normal renal function (p less than 0.001). These findings suggest that the high prevalence of hypertension in chronic glomerulonephritis is related to the declining renal function. On the other hand, hypertension appears to represent a bad prognostic sign.

Age Factors↗

[Selective IgA deficiency in systemic lupus erythematosus (author's transl)].

The case of a 23 year-old female with a diagnosis of systemic lupus erythematosus associated to selective IgA deficiency is reported. The patient persistently had serum IgA levels below 0.05 mg/dl, while the remaining serum immunoglobulins were normal. No salivary IgA was detected, and the karyotype disclosed no abnormalities of the chromosome 18. In the in vitro immunological study a normal number of B and T lymphocytes was found, and decreased production of all surface immunoglobulins was observed.

Adult↗

[Upper urinary tract fistulas in renal transplantation].

237 kidney transplants were performed in our department in a period running from November 1979 to October 1986. Out of this total number of transplants we analyzed the incidence of fistulas of the upper urinary tract, which in our series is 3.3%. Following a study protocol of these patients referring to multiple parameters, we conclude that in our series fistulas of the upper urinary tract appear precociously (less than 45 days post-transplant) and in connection with acute rejection episodes (high doses of steroids). On the basis of anatomopathological criteria we establish that its treatment has to be surgical and a meticulous surgical extraction technique is essential for its prevention.

Adolescent↗