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Biomedical subjects

L P Fischer

Publications and source records attributed to L P Fischer.

At least 37 records · Page 2Linked to original sources

[Fracture of the odontoid process (author's transl)].

102 cases of fractures of the odontoid process have been seen by the author - 73 recent cases and 29 old ones. It was important to distinguish basal fractures (29 cases), which all united after conservative treatment by reduction and skull traction for six weeks followed by a plaster cast for six to eight weeks, and fractures of the body (44 cases). 41 body fractures were treated conservatively, of which 6 died and only 20 united. The authors consider that treatment by skull traction must always be tried. An eventual indication for surgery can be made at about the 20th day if displacement is found to be present in spite of treatment. Fusion in these cases must be limited to C1-C2. It is best obtained by a combination of wiring and grafting.

Adolescent↗

[Resistance to traction of the periarticular ligaments and tendons of the knee].

The authors present a methodical study concerning traction strength of the ligaments and the periarticular tendons of the knee. The straining potential and the mechanical strength of these elements are made clear. This study permits applications in chronic laxities of the knee by giving the mechanical value of the different kinds of tendon reconstruction.

Elasticity↗

[Anatomical and histological study of osteochondral and costal cartilage autografts in the dog].

A macroscopic and microscopic anatomical study of the knees of 10 Beagles showed that thin osteo-chondral autografts taken from another joint healed perfectly macroscopically and almost perfectly histologically, if they fitted very well (figure 2). Rib cartilage grafts fitted perfectly to a dog's knee were not successful unless the perichondrium was turned towards the bone, in which case cartilage proliferated on the surface (figure 4). There was very little loss of substance but trans-chondro-osseus perforation also revealed a chondrogenic mode (figure 4). No trace was found in the literature of work concerning a comparison of these two types of grafts in the same experiment.

Animals↗

[Lumbar venography in the diagnosis of disc herniation (author's transl)].

The authors have performed lumbar venography on 120 occasions in patients with low back pain. In 58 patients in whom the herniated disc was confirmed, the result of venography was positive and the localisation was precise in 67 cases. It is concluded that the method is safe, reliable and allows precision in diagnosis to allow better selection for surgical treatment. The examination is particularly useful in recurrent sciatica, fractures of the lumbar spine, recent or old, and in spinal stenosis. It may be associated with discography when the result is not clear cut.

Arthritis↗

[Morphometry of the femoral head in the rabbit. Surface appearance of the acetabulum after femoral prosthesis].

An anatomical study has been achieved on 42 upper extremities of adult rabbit's thigh bones. Three types of prostheses have been perfected in order to analyse the reactions of the cartilage and of the subchondral bone when confronted with these implants. The animals were sacrificed at different intervals. The state of the acetabulum surface has been studied according to macroscopic and microscopic criteria. Three methods converge and agree in showing an arthrosis type of reaction with regard to the non operated controlateral articulation.

Acetabulum↗

[Arterial vascularization of human bones].

Analytical study of the arterial vascularization of bones in man. In practice, all the bones were studied with the exception of the skull. It is an original study using micro-angiography with micropaque. This study is of value in diagnosis of the pathogenesis of certain bone conditions and in traumatologic and orthopaedic therapy. A number of problems remain, in particular venous vascularization, micro-circulation in cartilage or in the sub-chondral zone and, lastly, the dynamic aspects of this type of bony circulation. Further research will be directed towards these fields.

Angiography↗

[Combination of methylmethacrylate (acrylic cement) and antibiotics. Bacteriologic and mechanical study].

The authors report the results of a study about the association of acrylic cement with antibiotics. Three cements have been tested: Simplex, CMW, Palacos, with 14 different antibiotics. A series of experiments has been carried out in three phases: a macroscopic study of the polymerisation of the mixture; in vitro bacteriological studies; and mechanical studies (trials of resistance to traction, flexion, shock measuring the modulus of elasticity and hardness). In vivo bacteriological testings have been carried out on 10 patients. It has come out from this study that the polymerisation of cement, usually does not destroy antibiotics which remain active and that the mechanical properties of cement are modified in sundry manners. All additions of tested antibiotics modifie mechanical properties by about 25 p. 100 but some additions seem to be preferable. Improvements must still be made and confirmed by this type of research.

Ampicillin↗

[Arterial vascularization of the os coxae].

Study of the arterial vascularization of the coxal bone by microangiographic methods. Nutritive and periosteal blood-vessels come from Iliaca interna and Iliaca externa arteries. The ilium is vascularized by the Ilio-lumbalis artery which is a nutritive blood vessel. A eriosteal vascularization also exists. Ischium and pubis have a periosteal vascularization. Blood vessels are oriented toward the sus-acetabulum area where many anastomoses exist.

Angiography↗