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Biomedical subjects

L P Gavriushova

Publications and source records attributed to L P Gavriushova.

At least 19 recordsLinked to original sources
PubMed1991

[Value of extracorporeal radioimmunoassay in children with nephrotic syndrome].

Extracorporeal radioimmune techniques were employed to study gonadotropic and sex hormones renin and beta 2-microglobulin in patients with nephrotic glomerulonephritis. The hypophyseal and gonadal system showed alterations which were dependent on the disease gravity. The level of renin and beta 2-microglobulin correlated first of all with renal function.

Child↗
PubMed1990

[The function of the hypophyseal-gonadal system in different variants of glomerulonephritis in children].

A total of 28 children with different varieties of glomerulonephritis were examined for the pituitary-gonadal system (PGS). The examination included measurements of follicle-stimulating and luteinizing hormones, prolactin, estradiol, progesterone and testosterone. To define standards of the content of the hormones under study, 45 children of the control group were examined. The relationship was analyzed between the content of hormones and the disease activity and gravity. The most active phase of glomerulonephritis was characterized by maximal alterations in the content of pituitary and gonadal hormones. The content of the latter ones appeared to be considerably changed in patients with the mixed pattern of glomerulonephritis, attesting to profound functional derangements in the PGS. The intensity of those derangements was determined by the severity of the pathological process.

Adolescent↗
PubMed1990

[The echocardiographic assessment of heart activity in paroxysmal tachycardia in children].

The echocardiograms of 42 children were examined during paroxysmal tachycardia attacks, as well as 15 minutes and 5 days after them. During paroxysms the electrical and mechanical cardiac activity gets dissociated, the end diastolic volume, the stroke index and ejection fraction decrease which is determined by the reduction of the volume load of the left ventricle because of the shortening of the diastolic phase of the cardiac cycle and the lack of the effective systole of the atria. The late diastolic opening of the mitral valve could not be recorded on the echocardiogram. During the interictal period, the most significant disorders of the cardiodynamics and alterations in the anatomical parameters were discovered in senior children suffering from paroxysmal tachycardia for 3 to 5 years and more.

Adolescent↗
PubMed1990

[Use of xidifon for prevention and treatment of nephropathies with metabolic disorders in children].

Xydofon was applied to the treatment of 68 children suffering from different renal diseases associated with metabolic disorders. The latter ones involved oxaluria (28 children), uraturia (17 children), cystinuria (14 children), and phosphaturia (9 children). To appraise the action of xydofon, use was made of the indicators of membranolysis, cellular homeostasis of calcium, lipid peroxidation, and of the level of beta 2-microglobulin in urine. The results obtained indicate that xydofon can be used as an effective remedy for the treatment of children suffering from nephropathies associated with metabolic disorders.

Adolescent↗
PubMed1985

[Radioimmunologic studies of glomerulonephritis in children].

Proceeding from a radioimmunoassay of various biologically active substances in the blood and urine (ACTH, cortisol, FSH, LH, prolactin, progesterone, estradiol, plasma renin activity and beta 2-microglobulin) of 220 children with glomerulonephritis change of all indices with relation to the type and gravity of glomerulonephritis as well as renal function was revealed. The nature of influence on corticosteroid and immunosuppressive therapy was shown. The authors consider it appropriate to use the determination of biologically active substances in the blood and urine for a more profound estimation of a child's status.

Adrenal Cortex Hormones↗