Biomedical subjects

L P Kruger

Publications and source records attributed to L P Kruger.

4 recordsLinked to original sources

PubMed1999

Paintball ocular injuries.

INTRODUCTION: Six cases of ocular injury following paintball injuries sustained during war games are described. A CO2-powered rifle shoots a 14 mm plastic-coated paintball at participants. The muzzle velocity of the gun is 250 ft/sec (76 m/sec). Locally manufactured paintballs are harder than the more expensive imported varieties and may account for the severity of our reported injuries. METHOD: Six patients presented to a retinal specialist with various ocular injuries, predominantly of the posterior pole. RESULTS: All patients were young males. There were no cases of ocular penetration. A variety of retinal pathologies was noted, with three cases requiring surgery; however this did not significantly improve the visual outcome. CONCLUSIONS: These cases highlight the severe ocular injuries that may occur from paintball injuries. Recommendations to avoid ocular injury are made.

Adolescent↗

PubMed1990

Prophylaxis of aphakic cystoid macular edema without corticosteroids. A paired-comparison, placebo-controlled double-masked study.

Prior investigations have reported that topical nonsteroidal anti-inflammatory drug (NSAID) therapy prevents the development of postoperative angiographic signs of angiographic cystoid macular edema (CME). However, these studies include concurrent use of corticosteroids. The current study reports therapeutic efficacy for ketorolac ophthalmic solution (an NSAID) in the prophylaxis of angiographic aphakic CME (ACME) after cataract surgery without concurrent corticosteroids for the first time. Fifty patients with bilateral cataracts were enrolled in this placebo-controlled, paired-comparison, double-masked study. Eleven patients had evidence of angiographic ACME on postoperative day 40. Two of these patients demonstrated bilateral ACME, one patient had ACME in the NSAID-treated eye, and eight patients demonstrated ACME in the placebo-treated eye. This is a statistically significant difference favoring drug treatment. The signs of anterior ocular inflammation were greater in the eyes with ACME. This study suggests prophylactic treatment of ACME may be possible without the risks of concurrent corticosteroid toxicity. In addition, a higher incidence of ACME in black patients (22%) is observed in this study than has been recognized previously.

Adult↗

PubMed1988

Quantitative assessment of postsurgical breakdown of the blood-aqueous barrier following administration of 0.5% ketorolac tromethamine solution. A double-masked, paired comparison with vehicle-placebo solution study.

Preoperative and serial postoperative anterior chamber fluorophotometry were performed after oral administration of fluorescein sodium in patients undergoing extracapsular cataract extraction and posterior chamber intraocular lens insertion. The administration of topical 0.5% ketorolac tromethamine solution before and after surgery markedly decreased the breakdown of the blood-aqueous barrier compared with vehicle-placebo solution administration at each time period, as measured by fluorophotometry. Corticosteroids were not given to any patients throughout the duration of the study. These fluorophotometric results correlated well with slit-lamp observations of postoperative ocular inflammation. Both ketorolac and vehicle were well tolerated by patients. No effects on intraocular pressure were seen with ketorolac administration. This study suggests that ketorolac ophthalmic solution is effective and safe as a nonsteroidal anti-inflammatory agent for topical use following cataract surgery and intraocular lens implantation.

Adult↗

PubMed1988

Trichomoniasis and campylobacteriosis in bulls in the Republic of Transkei.

Trichomonas foetus was demonstrated in 23/87 (26.4%) and Campylobacter fetus in 25/87 (28.7%) of bulls tested in Transkei. A total of 16/87 (18.39%) of bulls tested were positive for both Trichomonas foetus and Campylobacter fetus. Bulls from 14 sites in Transkei were tested and Trichomonas foetus was isolated at 9 of these sites. Campylobacter fetus was isolated at 10 of the 14 sites. The results indicate that both Trichomonas foetus and Campylobacter fetus are widespread throughout the cattle population in the Republic of Transkei and may account for infertility problems.

Age Factors↗