Biomedical subjects

L P Palfrey

Publications and source records attributed to L P Palfrey.

2 recordsLinked to original sources

PubMed1989

The effect of machine speed on the consolidation of four directly compressible tablet diluents.

The reduction in porosity of a powder bed on compression was found to be a function of the velocity of the punch of the press. Substances which consolidated principally by fragmentation showed relatively little velocity dependence. However, the more important deformation was in a powder's consolidation mechanism, the greater the dependence on punch velocity and hence tablet press speed.

Chemistry, Pharmaceutical↗

PubMed1987

Punch velocities during the compaction process.

Velocities achieved by the upper punch of an eccentric tablet press during compaction have been compared with those predicted by equations describing the movement of the punch in an empty die. Up to the point of maximum punch penetration, actual speeds are invariably less than the predicted speed, the magnitude of the deceleration being determined by the machine speed and applied force. As the punch withdraws from the die, its speed can exceed that predicted on theoretical grounds, due to the elastic expansion of the tablet assisting punch ejection.

Elasticity↗